Publications by authors named "Ben Cromarty"
Article Synopsis
- * None of the participants experienced a recurrence of PRT or significant changes in kidney function or related biomarkers during the study.
- * The findings indicate that TAF is a safe and effective treatment choice for those at risk of developing PRT.
Background: Proximal renal tubulopathy (PRT) is an infrequent complication of tenofovir disoproxil fumarate (TDF). It remains to be established whether tenofovir alafenamide (TAF) can be safely administered to individuals who experienced PRT on TDF.
Methods: Individuals with a history of TDF-associated PRT and current estimated glomerular filtration rate (eGFR) over 30 mL/min/1.
Background: Patient and public involvement (PPI) in clinical trials aims to ensure that research is carried out collaboratively with patients and/or members of the public. However, current guidance on involving clinical trial participants in PPI activities is not consistent.
Methods: We reviewed the concept of participant involvement, based on our experience.
Background: Patient and public involvement (PPI) in studies carried out by the UK Medical Research Council Clinical Trials Unit (MRC CTU) at University College London varies by research type and setting. We developed a series of case studies of PPI to document and share good practice.
Methods: We used purposive sampling to identify studies representing the scope of research at the MRC CTU and different approaches to PPI.