Publications by authors named "Belson Kutambe"
Article Synopsis
- Researchers have identified the first two enterotoxigenic E. coli (ETEC) genomes from Malawi, isolated in 2014.
- These genomes were taken from the feces of children who were infected but did not show symptoms.
- The genomes contain a version of the heat-labile toxin found in pigs, but lack any recognized ETEC colonization factors.
Background: Compared to the abundance of clinical and genomic information available on patients hospitalised with COVID-19 disease from high-income countries, there is a paucity of data from low-income countries. Our aim was to explore the relationship between viral lineage and patient outcome.
Methods: We enrolled a prospective observational cohort of adult patients hospitalised with PCR-confirmed COVID-19 disease between July 2020 and March 2022 from Blantyre, Malawi, covering four waves of SARS-CoV-2 infections.
Article Synopsis
- The study investigates COVID-19 patient outcomes and viral lineages in Malawi, highlighting a lack of data from low-income countries.
- Conducted from July 2020 to March 2022, researchers analyzed 314 hospitalized patients, discovering distinct variants during each wave—B.1, Beta, Delta, and Omicron.
- Results indicated that patients during the Delta wave had higher mortality rates compared to earlier waves, while those infected with Omicron showed fewer chronic conditions and required less intensive treatment.