[Quality of life of patients with ischemic stroke in the vertebrobasilar system].

We studied the characteristics of quality of life in patients in the acute and recovery phase of ischemic stroke in the vertebral-basilar basin due to hypertensive disease as the leading risk factor for the disease. The rates of basic daily activities on a Barthel scale, cognitive functions on the MMSE, physical and mental components of health on the SF-36 were significantly reduced in patients with acute ischemic stroke. The improvement in functional and cognitive impairments was observed during the first year after stroke.

[The results of Russian multicenter open-label observational study of the efficacy and safety of мelaxen (melatonin) for the treatment of disordered sleep in patients with chronic cerebral ischemia].

The results of the multicenter open-label observational study of the efficacy and safety of the Melaxen (melatonin) for the treatment of disordered sleep in patients with chronic cerebral ischemia are presented. 2062 patients were studied with the use of subjective psychometric scales: subjective sleep characteristics scale, sleep apnea screening questionnaire, Epworth sleepiness scale, hospital anxiety and depression scale. Mean age of patients was 55.

[Diagnosis and treatment of pelvic disorders in patients with multiple sclerosis].

Pelvic dysfunction is a frequent severe manifestation of multiple sclerosis (MS). Basing on the experience in management of 70 MS patients with pelvic affection, we developed an algorithm of outpatient care for such patients which involves neurological, urological and gastroenterological assistence.

[Complex treatment of epilepsy with phenotropil].

Effect of phenotropil in combination with anticonvulsant drugs on the course of different forms of epilepsy and EEG parameters has been studied. Patients of a main group (31 patients) received phenotropil, along with antiepileptic drugs (AEP), in dosage 100 mg daily during 2 months. Effect of the therapy was compared to the patients of comparison group (30 patients) treated with AEP only.

The clinical diagnosis of cranial nerve injuries at operations on the carotid arteries.

Operation on the carotid arteries (CA) prevent strokes in patients with occlusions and stenoses of these arteries. We have worked out the measures for preventing perioperative strokes. During interventions on the CA, iatrogenic injuries to the cranial nerves (CN) are paid little attention.

[The role of biogenic amines in the mechanism of uterine hemorrhage in uterine myoma].

Function of the adrenosympathetic system has been assessed in 103 patients with uterine myoma. Levels of biogenic amines (adrenaline, noradrenaline, histamin) were determined in uterine tissues using spectrofluorometry. It was found out that storage of vasoactive mediators in the uterine tissue represents a mechanism of uterine bleedings in patients with uterine myoma.