Decreasing the Bond Order between Vanadium and Oxo Ligand to Form 3d Schrock Carbynes.

Preserving vanadium in a high oxidation state during chemical transformations can be challenging due to the oxidizing nature of V(+5) species. Oxo and similar isoelectronic ligands have been utilized to stabilize V(+5) by extensive π-donation. However, decreasing the bond order between V and the oxo ligand often results in a reduction of the metal center.

[Intrathecal chemotherapy for leptomeningeal metastases in patients with breast cancer].

Unlabelled: Leptomeningeal metastases are lesions of brain and/or spinal cord sheaths by tumor cells. They occur in 5% of patients with solid tumors, although autopsies reveal these lesions much more often (10-20% of cases). Leptomengeal metastases are an unfavorable prognostic factor.

Dependence of rhythmic activity and oddball effects in the rat cortex on the depth of sedation during dissociative anesthesia.

The reactions to novelty manifesting in mismatch negativity in the rat brain were studied. During dissociative anesthesia, mismatch negativity-like waves were recorded from the somatosensory cortex using an epidural 32-electrode array. Experimental animals: 7 wild-type Wistar rats and 3 transgenic rats.

[Evaluation of the accuracy of modern intraocular lens calculation formulas when optical biometry is not possible].

Purpose: This study evaluates the accuracy of modern intraocular lens (IOL) calculation formulas using axial length (AL) data obtained by ultrasound biometry (UBM) compared to the third-generation SRK/T calculator.

Material And Methods: The study included 230 patients (267 eyes) with severe lens opacities that prevented optical biometry, who underwent phacoemulsification (PE) with IOL implantation. IOL power calculation according to the SRK/T formula was based on AL and anterior chamber depth obtained by UBM (Tomey Biometer Al-100) and keratometry on the Topcon KR 8800 autorefractometer.

[Reasonability of accounting for gender in intraocular lens power calculation].

Purpose: The study assesses the influence of gender on the accuracy of intraocular lens (IOL) power calculation by formulas SRK/T, Barrett Universal II (BUII), Ladas super formula (LSF), Hill RBF (RBF) and Kane.

Material And Methods: The study enrolled 214 patients (106 men and 108 women) who underwent cataract phacoemulsification (PE). Optical biometry was performed on IOL-Master 500.

Mononuclear Four-Coordinate Bis-Fluoride Bis-NHC Complexes of Chromium(II), Iron(II), and Cobalt(II).

The reaction between silylamido complexes of Cr(II), Fe(II), and Co(II) and IMes·2HF salt in the presence of IMes (IMes = 1,3-dimesitylimidazol-2-ylidene) led to isolation of Cr(IMes)F (), Fe(IMes)F (), and Co(IMes)F (). X-ray structural studies revealed that adopts square planar geometry, while and have distorted tetrahedral geometry. Magnetic susceptibility studies of , , and were consistent with high-spin complexes, = 2 for / and = 3/2 for .

First Detection of Potato Spindle Tuber Viroid in Natural Isolates of Potato Blight Agent Phytophthora infestans.

Phytophthora infestans is the oomycete that causes potato blight, an important disease. The potato spindle tuber viroid (PSTVd) is a dangerous pathogen of many plants, including potato. We have previously shown that PSTVd can be transmitted from infected potato plants into the Ph.

[Clinical features and treatment of endophthalmitis after cataract surgery].

Purpose: The study analyzes the frequency of acute endophthalmitis occurrence after cataract surgery, the risk factors, characteristic symptoms, and the effectiveness of peri-operative prevention measures.

Material And Methods: The study retrospectively analyzed 59 670 cases of patients operated for cataract in 2017-2021. To prevent infections, patients received four instillations of third generation fluoroquinolone (quinolone antibiotic) in the course of two days prior to cataract phacoemulsification (PE), and two instillations immediately (1 hour and 30 minutes) before the surgery; three-minutes treatment of the cornea, conjunctival sac and periocular skin with 5% povidone iodine before the surgery; and as the last step of surgery, patients received subconjunctival injection of 0.

Combustion Synthesis and Reactive Spark Plasma Sintering of Non-Equiatomic CoAl-Based High Entropy Intermetallics.

The present work reports the direct production of a high-entropy (HE) intermetallic CoNiFeCrAl material with a B2 structure from mechanically activated elemental powder mixtures. Fast and efficient combustion synthesis (CS), spark plasma sintering (SPS), and reactive SPS (RSPS) methods were used to synthesize the HE powders and bulks. The formation of the main B2 phase along with some amounts of secondary BCC and FCC phases are reported, and L12 intermetallic (CS scheme) and BCC based on Cr (CS + SPS and RSPS schemes at 1000 °C) were observed in all samples.

Different sensitivity to anesthesia according to ECoG data in dopamine transporter knockout and heterozygous rats.

Dopamine in the brain is involved in many important functions, including the regulation of wakefulness. There is also some evidence suggesting that the dopamine function is crucial in anesthetic function. The state of anesthesia is characterized by a change in the level of consciousness and a change in brain electrical activity.

[Alternative method of intraocular lens power calculation in eyes with short axial length].

Purpose: To develop an alternative method of intraocular lens (IOL) power calculation in eyes with mature cataract and axial length (AL) of less than 22.0 mm using modern formulas Barrett Universal II and Hill RBF.

Material And Methods: The study enrolled 41 patients (41 eyes) who underwent phacoemulsification (PE).

Late-onset Fabry disease: the cardiac sequela.

We describe a patient with Fabry disease (FD) who initially presented with atrial fibrillation without left ventricular hypertrophy (LVH) 14 years before being correctly diagnosed with FD. In the interim, he survived a myocardial infarction complicated by ventricular fibrillation, and his severe LVH was misdiagnosed as sarcomeric hypertrophic cardiomyopathy. In the following 4 years, he developed proteinuric kidney disease, neuropathy, sensorineural hearing loss and gastrointestinal symptoms.

Detecting Examinees With Item Preknowledge on Real Data.

Recently, Belov & Wollack (2021) developed a method for detecting groups of colluding examinees as cliques in a graph. The objective of this article is to study how the performance of their method on real data with item preknowledge (IP) depends on the mechanism of edge formation governed by a response similarity index (RSI). This study resulted in the development of three new RSIs and demonstrated a remarkable advantage of combining responses and response times for detecting examinees with IP.

[Calculation of intraocular lens power after trabeculectomy].

Purpose: To assess biometric changes in eyes after trabeculectomy (TE) and its impact on refractive outcomes of phacoemulsification (PE) in order to determine the corrections for calculation of intraocular lens (IOL) power.

Material And Methods: The study included two groups of patients: the 1 group consisted of 116 patients who were assessed by optical biometry (IOL-Master 500) for mean biometric values before and after TE; the 2 group included 31 patients with history of TE (study subgroup) and 47 individuals without glaucoma (control subgroup) who underwent PE with subsequent comparison of IOL calculation accuracy.

Results: There was significant axial length (AL) shortening in the 1 group from 23.

Photoelectromagnetic Effect Induced by Terahertz Laser Radiation in Topological Crystalline Insulators PbSnTe.

Topological crystalline insulators form a class of semiconductors for which surface electron states with the Dirac dispersion relation are formed on surfaces with a certain crystallographic orientation. PbSnTe alloys belong to the topological crystalline phase when the SnTe content exceeds 0.35, while they are in the trivial phase at < 0.

Effect of capsular tension ring implantation during phacoemulsification on postoperative refraction.

Purpose: To assess refractive outcomes of phacoemulsification (PE) with additional capsular tension ring (CTR) implantation.

Material And Methods: In total, 37 eyes of 37 patient who underwent PE with intraocular lens (IOL) implantation were divided into 2 groups: study group (n = 18) with CTR co-implantation (inclusion criteria was preoperative irido-phacodonesis) and control group (n = 19) without CTR. Optical biometry (IOL-Master 500) was performed for each patient before PE.

[A rare case of gerniation and incarceration of the gallbladder].

The authors report a rare case of herniation and incarceration of the gallbladder at the site of abdominal drainage tube deployment in a patient undergoing treatment for aortic valve disease. An incarcerated postoperative ventral hernia was confirmed by contrast-enhanced CT of the abdomen. Emergency surgery was not indicated due to spontaneous reduction, short duration of incarceration and no peritoneal signs.

[Optimization of intraocular lens power calculation in pseudoexfoliation syndrome].

Purpose: To assess the impact of pseudoexfoliation syndrome (PEX) on the accuracy of intraocular lens (IOL) power calculation.

Material And Methods: The study included 243 patients who underwent phacoemulsification (PE); they were divided into the control (no PEX signs, =131) and study (signs of PEX, =112) groups. Barrett Universal II formula was used for IOL calculation by optical biometry (IOL-Master 500).

Design of gp120 HIV-1 entry inhibitors by scaffold hopping via isosteric replacements.

We present the development of alternative scaffolds and validation of their synthetic pathways as a tool for the exploration of new HIV gp120 inhibitors based on the recently discovered inhibitor of this class, NBD-14136. The new synthetic routes were based on isosteric replacements of the amine and acid precursors required for the synthesis of NBD-14136, guided by molecular modeling and chemical feasibility analysis. To ensure that these synthetic tools and new scaffolds had the potential for further exploration, we eventually tested few representative compounds from each newly designed scaffold against the gp120 inhibition assay and cell viability assays.

Graph Theory Approach to Detect Examinees Involved in Test Collusion.

Test collusion (TC) is sharing of test materials or answers to test questions before or during the test (important special case of TC is item preknowledge). Because of potentially large advantages for examinees involved, TC poses a serious threat to the validity of score interpretations. The proposed approach applies graph theory methodology to response similarity analyses for identifying groups of examinees involved in TC without using any knowledge about parts of test that were affected by TC.

Olefin Metathesis by First-Row Transition Metals.

Catalytic olefin metathesis based on the second- and third-row transition metals has become one of the most powerful transformations in modern organic chemistry. The shift to first-row metals to produce fine and commodity chemicals would be an important achievement to complement existing methods with inexpensive and greener alternatives. In addition, those systems can offer unusual reactivity based on the unique electronic structure of the base metals.

Design, synthesis, and antiviral activity of a series of CD4-mimetic small-molecule HIV-1 entry inhibitors.

We presented our continuing stride to optimize the second-generation NBD entry antagonist targeted to the Phe43 cavity of HIV-1 gp120. We have synthesized thirty-eight new and novel analogs of NBD-14136, earlier designed based on a CHOH "positional switch" hypothesis, and derived a comprehensive SAR. The antiviral data confirmed that the linear alcohol towards the "N" (C4) of the thiazole ring yielded more active inhibitors than those towards the "S" (C5) of the thiazole ring.

Ring-Closing Olefin Metathesis Catalyzed by Well-Defined Vanadium Alkylidene Complexes.

Vanadium-based catalysts have shown activity and selectivity in ring-opening metathesis polymerization of strained cyclic olefins comparable to those of Ru, Mo, and W catalysts. However, the application of V alkylidenes in routine organic synthesis is limited. Here, we present the first example of ring-closing olefin metathesis catalyzed by well-defined V chloride alkylidene phosphine complexes.

Risk score for predicting abdominal complications after coronary artery bypass grafting.

Background: Although early abdominal complications after coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) are rare, the associated mortality remains high.

Aim: To develop a risk score for the prediction of early abdominal complications after CABG with CPB.

Methods: This retrospective study was performed in the Federal State Budgetary Establishment "Federal Center of Cardiovascular Surgery" of the Ministry of Health of Russia (the city of Chelyabinsk) and included data of 6586 patients who underwent CABG with CPB during 2011-2017.

Stereospecific Ring-Opening Metathesis Polymerization of Norbornene Catalyzed by Iron Complexes.

Developing well-defined iron-based catalysts for olefin metathesis would be a breakthrough achievement in the field not only to replace existing catalysts by inexpensive metals but also to attain a new reactivity taking advantage of the unique electronic structure of the base metals. Here, we present a two-coordinate homoleptic iron complex, Fe(HMTO) [HMTO=O-2,6-(2,4,6-Me C H ) C H ], that is capable of performing ring-opening metathesis polymerization of norbornene to produce highly stereoregular polynorbornene (99 % cis, syndiotactic). The use of heteroleptic Fe(HMTO)(RO) [RO=(CH ) CF CO, CH (CF ) CO, or Ph(CF ) CO] prepared in situ significantly increases the polymerization rate while preserving selectivity.