Publications by authors named "Bellossi A"

In previous studies it has been shown that exposure of mice to a 12-Hz 6 mT unipolar square pulsed magnetic field (PMF) suppressed the excess of weight due to application of 1st cold-pressure sunflower oil. This time we considered the effect of oil and/or PMF on the growing curves lifespans of mice. The exposure took place for 30 min 5 days a week, from the 7th week of life to death.

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Background: Liver is a crucial organ in metabolism. For instance liver is the main source of circulating lipoproteins.

Methods: In this paper cholesterol and triglyceride plasma levels were measured in male rats previously exposed to pulsed magnetic fields (PMF) used in therapy.

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Liver cell necrosis was induced in rats by a galactosamine injection. Cell death was due to an increase of Ca++ intracellular levels and was also under the control of genes. Rats were then either exposed or not to a 6 mT 100 HZ pulsed magnetic field (PMF) and they either received or not methylsilane-triol injections.

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In a previous work a decrease in cholesterol and triglyceride plasma levels was observed in rats 24 hours after their exposure to a 12 Hz 6 mT pulsed magnetic field (PMF). This time, a study of intensity effects of a 12 Hz PMF for a sixty-minute exposure and of length of exposure for a 12 Hz 6 mT PMF took place. Non-linear effect-dose relationships were observed for the PMF intensity as well as for the length of exposure used.

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This work was undertaken to check the effects of 460 Hz pulsed magnetic fields (PMF) on the growth curves of mice, and to observe any possible long term effect. Effects on the growth curves have already been shown in young female AKR mice. Eight-week-old Swiss female mice underwent, until death, a twice weekly a one-hour-exposure to a 460 Hz 6 mT PMF.

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Pulsed magnetic fields (PMF) have already proved to have a certain influence not only on leucocytes in vitro but also on thymocytes in vivo. C3H/Bi tumoral female mice were either exposed to 12 Hz or 460 Hz, and to 6, 9 or 20 mT PMF just two weeks after the tumors had appeared and this until the moment they died. Actually, all the survival times as well as the average weights of spleens lungs, and tumors were then taken into account at the very death of the mice.

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For thirty minutes Swiss mice were exposed to a 60 G 12 Hz or a 460 Hz pulsed magnetic field. The blood-brain flow was then calculated thanks to an i.v.

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AKR mice were exposed to a 6 mT, 12 Hz or 460 Hz pulsed magnetic field (PMF) 30 minutes twice a week. The exposure took place in utero and/or during the life span for four consecutive generations. The adult mice exposed to the 460 Hz PMF only after the birth time were lighter than the controls; for the two frequencies the decrease in weight with the ageing was less pronounced than in the controls.

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AKR mice were exposed to a 6 mT, 12 Hz or 460 Hz pulsed magnetic field for 30 minutes twice a week. The exposure took place in utero and/or during the life span for five consecutive generations. For the exposure the grown-up mice were put into a container which caused a restraint stress.

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In a previous experiment, the exposure of tumoral C3H/Bi female mice to a 9 mT, 460 Hz pulsed magnetic field led to an increase in the length of survival in the late period of the disease; this might be due to a hampered metastatic process. In the present study 27 controls and 52 exposed mice were treated with the same protocol (a 10-minute exposure, 3 non-consecutive days a week, from 2-3 weeks after the tumors appeared until death) but with a 12 Hz PMF. In this experiment the 12 Hz PMF appeared to increase length of survival times in the early period of the disease.

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Leukemia-prone AKR mice were exposed twice a week to a 6 mT, 12 Hz or 460 Hz pulsed magnetic field for 30 min. If we take into account the five consecutive generations of mice, the above exposure actually took place in utero and, or during their life span. There was no difference in the incidence of leukemia or in the actuarial survival curves or in the average spleen or thymus weights.

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An exposure of adult mice to a pulsed magnetic field (PMF) increases thymus weight. In this work, thymic lymphocytes were studied by cellular electrophoresis because the proliferation and maturation of these cells is linked to an increase in their electrophoretic mobility (EM). Fifteen-week-old female Swiss mice were exposed for 30 min to a 6 mT PMF, 12 or 460 Hz in frequency, according to different modalities.

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The hypothesis that magnetic fields act only on deficient functions has been tested through the weight of the thymus in mice. The involution of the thymus in mice is known to begin early in life. It is marked by a decrease in weight.

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In a previous experiment an increase in the survival time of leukaemia-prone AKR mice was observed by exposure to a 600 mT or 800 mT static magnetic field when the mice were at least 200 days old. In this experiment 200-day-old-mice were exposed to a 6 mT pulsed magnetic field (PMF) for 30 minutes a day, twice a week until death. The frequency of the field was 12 Hz or 460 Hz.

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Female C3H/Bi mice develop spontaneous viral mammary carcinoma which can metastasize to the lungs. Two hundred and forty tumoral mice were either exposed to a toroïdal pulsed magnetic field, 12 Hz, 100 Hz or 460 Hz in frequency or used as controls. The exposure was mainly done 10 min.

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Young male rats were exposed to constant uniform magnetic fields of 400 and 800 millitesia (mT). No changes were observed in the body and in the pancreas weight, in the pancreatic insulin content and in the in vitro insulin release of Langerhans islets, in glucose and insulin plasma levels. The magnetic fields abolished the insulin effect on glucose uptake of diaphragms, but not on 1-14C-glucose oxidation.

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45Ca2+ efflux from neonatal isolated chick brains was measured. The brains were exposed to uniform or nonuniform static magnetic fields. The field intensity ranged from 200-900 mT.

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The influence of a life-long exposure to static magnetic fields (SMF) on the lifespan of female AKR mice which develop spontaneous lymphoblastic leukaemia was investigated. Exposure all day long to a circular SMF, 4.6 mT maximal intensity or 2 h a day, 5 consecutive days a week to a uniform SMF of 400 mT did not modify the lifespan of mice.

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Variations in the growth of animals from exposure to a magnetic field have been reported by several authors. In this study, young rats and mice were exposed daily to constant uniform magnetic fields. The strength of the field was 400, 600 or 800 mT.

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Modifications in brain functions after exposure to a constant magnetic field have been noted in animals. For some authors, the main factor is the action of magnetic fields on tissular water. The relaxation times obtained by proton nuclear magnetic resonance should therefore be modified.

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