[Interest of bone alkaline phosphatase in hemodialysis patients].

Background: The renal osteodystrophy represent a major complication in hemodialysis.

Aim: To evaluate the value of plasma bone-alkaline phosphatase (bAP) in the diagnosis of the type of renal osteodystrophy among hemodialysis patients and to seek a possible correlation between the bAP, total alkaline phosphatases (tAP) and the intact parathormone (iPTH).

Methods: We studied 67 chronic hemodialysis patients.

[Recurrent bilateral shoulder hand syndrome induced by phenobarbital].

Algodystrophy syndrome is characterized by pain, vasomotor disorders and/or trophic skin changes, without laboratory signs of inflammation. Among the etiological factors of this syndrome (trauma, cerebrovascular accident, diabetes mellitus..

[Allergic reactions to paracetamol].

Background: Paracetamol is an extensively used analgesic and antipyretic. Allergy to this drug is occasionally reported and is usually moderate.

Materials And Methods: We led a retrospective study of 119 cases of allergic reactions to paracetamol notified to the Tunisian centre of pharmacovigilance, between September 1990 and September 2000.

[Isoniazid acetylation in a group of Tunisian patients. Report of 620 patients].

Isoniazid is a first line antituberculosis drug metabolized mainly in the liver by the Nacetyltransferase. There are differences between individuals in acetylation metabolism. Subjects are thereby characterized as being rapid or slow acetylators.