Purpose: To determine the sensitivity and specificity of different retinal imaging combinations for the diagnosis of choroidal neovascularization (CNV) in age-related macular degeneration.
Methods: Patients aged 50 years or older referred for suspicious recent-onset CNV related to age-related macular degeneration were prospectively included for 6 months. Data recorded included color fundus photographs (CFPs), spectral domain optical coherence tomography (SD-OCT), and fluorescein angiography (FA) images.
Purpose: To describe an unusual feature in myopic eyes responsible for visual loss, which we call a dome-shaped macula.
Design: Retrospective, observational case series.
Methods: After observing isolated cases of dome-shaped macula, we analyzed optical coherence tomography (OCT) scans of 140 highly myopic eyes present in our OCT database to find similar cases.
Purpose: To characterize the evolution of serous retinal detachment (SRD) combined with diabetic macular edema (DME) using optical coherence tomography (OCT).
Design: Observational retrospective case series.
Methods: In our institution, 64 eyes of 40 diabetic patients who had SRD combined with DME were studied.
Purpose: Full-thickness macular hole associated with diabetic macular oedema is a rare feature and its pathogenesis remains incompletely elucidated. We report the occurrence of a full-thickness macular hole, documented with optical coherence tomography (OCT), in a patient with diabetic cystoid macular oedema treated by intravitreal triamcinolone injections.
Case Report: A 48-year-old woman with refractory diabetic cystoid macular oedema underwent successive intravitreal triamcinolone injections, which were followed by a progressive thinning of the neurosensory retina at the fovea, and then by a full-thickness macular hole, associated with a perifoveal posterior hyaloid detachment, visible on OCT.
Purpose: To assess the optical coherence tomography (OCT) characteristics of spontaneously closed macular hole (MH).
Design: Retrospective observational case series.
Methods: Among 510 consecutive eyes examined for an MH before surgery, we retrospectively identified 14 eyes in which the MH closed spontaneously before the operation.
Purpose: To determine the natural evolution and surgical indications of myopic foveoschisis (MF), which are still poorly documented, and the factors that predict poor prognosis.
Design: Retrospective observational case series.
Methods: Twenty-nine operated and nonoperated cases of MF (29 eyes of 23 patients) were studied.
Objective: To describe the changes observed with optical coherence tomography in group 2A idiopathic juxtafoveolar retinal telangiectasis.
Methods: We retrospectively reviewed the medical records of 13 patients (25 eyes). All eyes underwent optical coherence tomography examination consisting of 6 radial scans, fundus color photography, and fluorescein angiography.
Purpose: To prospectively compare the efficacy and safety of 4 vs 2 mg intravitreal triamcinolone acetonide (TA) injection for diabetic macular edema.
Design: Interventional case series.
Patients: Thirty-two patients with diabetic macular edema unresponsive to laser photocoagulation.
Purpose: To evaluate prospectively the efficacy and safety of one intravitreal injection of 4 mg triamcinolone acetonide for refractory diffuse diabetic macular edema.
Methods: Seventeen patients with bilateral diabetic macular edema unresponsive to laser photocoagulation. In all patients, one eye was injected, and the other served as a control.
Cataract surgery requires a satisfactory degree of mydriasis throughout the entire operation. A phase I, open-labelled, randomised, cross-over trial was conducted in 18 healthy volunteers to compare mydriasis obtained with subsequent administration of phenylephrine 10% and tropicamide 0.5% eyedrops or a new insoluble-matrix retropalpebral ophthalmic insert containing 5.
View Article and Find Full Text PDFPurpose: To use optical coherence tomography (OCT) to characterize the intraretinal changes associated with macular edema (ME) according to its etiology.
Design: Observational case series.
Methods: Seventy-eight eyes of 78 patients with ME were examined retrospectively by OCT, using the Humphrey 2000 OCT system (Humphrey Co.
Purpose: To study the vitreoretinal relationship in diabetic patients with and without diabetic macular edema (DME) using optical coherence tomography.
Design: Retrospective case-control study.
Methods: setting: Institutional practice.
Purpose: To assess the usefulness of optical coherence tomography (OCT) for better differential diagnosis of macular pseudoholes (MPH) and lamellar macular holes (LMH).
Design: Observational case series.
Methods: setting: Institutional practice.
Purpose: To develop a population model capable of describing the profile of the effect of intravitreal triamcinolone acetonide in the treatment of diabetic diffuse macular edema.
Methods: The results of 51 injections in 37 eyes (33 patients) with diffuse diabetic macular edema were studied, by using population pharmacokinetic-pharmacodynamic modeling, without triamcinolone concentration measurements. This approach was supported by the pharmacokinetic hypothesis that the intravitreal triamcinolone concentration decreases in accordance with an exponential biphasic equation.
Objective: To evaluate prospectively the efficacy and safety of 1 intravitreal injection of 4 mg of triamcinolone acetonide for refractory diffuse diabetic macular edema.
Design: Interventional case series.
Participants: Fifteen patients with bilateral diabetic macular edema unresponsive to laser photocoagulation.
Purpose: To evaluate the efficacy of intravitreal triamcinolone in refractory pseudophakic cystoid macular edema.
Design: A prospective, interventional case series.
Methods: Three eyes of three patients with longstanding pseudophakic cystoid macular edema following uncomplicated cataract surgery, refractory to any medication, were treated with 8 mg of intravitreal triamcinolone.
Purpose: To report the use of optical coherence tomography (OCT) for evaluation of diffuse diabetic macular edema (DME) before and after vitrectomy.
Design: Interventional case series.
Methods: A retrospective study was made of 15 consecutive eyes of 13 patients that had vitrectomy for diffuse DME and OCT preoperatively and postoperatively.
Purpose: To describe the characteristics and evolution of macular retinoschisis in high myopia observed by optical coherence tomography (OCT).
Design: A consecutive, retrospective, observational case series.
Methods: Twenty-one highly myopic eyes (mean refractive error, -15.