Young patients with benign anal diseases and rectal bleeding: should a colonoscopy be performed?

Background And Aim: There is no consensus whether a colonoscopy should be recommended for patients under 50 years of age who present with both anal bleeding and benign anal diseases. The aim of this study is to evaluate the effectiveness of colonoscopy to detect neoplastic lesions in this specific group of patients.

Methods: A prospective study analyzing the results of colonoscopies performed in patients younger than 50 years of age who reported a rectal bleeding and also had a diagnosis of benign anal disease at first clinical visit.

Fluorescent test accurately predicts leak of ischemic colon anastomosis in rats.

Purpose:: To investigate if fluorescein fluorescent test can predict dehiscence in a model of ischemic colonic anastomosis in rats.

Methods:: This experimental controlled trial randomly assigned 55 rats to four groups. Anastomoses were performed in non-ischemic colon segments (control group) and in ischemic colon segments measuring 1, 2 or 3 cm long (groups 1, 2 and 3, respectively).