Publications by authors named "Belinda Pik-yuen Cheung"
Article Synopsis
- MG7 is a monoclonal antibody specifically designed for detecting gastric cancer and shows high sensitivity and specificity, but its target antigen has not been identified yet.
- Western blot analysis revealed that MG7 binds to two proteins around 35 kDa in human gastric cancer cell lines, which were identified as the hnRNP A2/B1 protein using a proteomic approach.
- Further analysis showed hnRNP A2/B1 is found only in the nucleus of cells and is elevated in 4 out of 5 gastric cancer tissue samples compared to normal stomach tissue.
