Transfer dynamics of multi-resistance plasmids in Escherichia coli isolated from meat.

Resistance plasmids are crucial for the transfer of antimicrobial resistance and thus form a matter of concern for veterinary and human healthcare. To study plasmid transfer, foodborne Escherichia coli isolates harboring one to five known plasmids were co-incubated with a general recipient strain. Plasmid transfer rates under standardized conditions varied by a factor of almost 106, depending on the recipient/donor strain combination.

Multiplication of upon Exposure to a Beta-Lactam Antibiotic Results in a Transferable Transposon in .

Plasmids play a crucial role in spreading antimicrobial resistance genes. Plasmids have many ways to incorporate various genes. By inducing amoxicillin resistance in , followed by horizontal gene transfer experiments and sequencing, we show that the chromosomal beta-lactamase gene is multiplied and results in an 8-13 kb contig.