Endothelium-derived microparticles from chronically thromboembolic pulmonary hypertensive patients facilitate endothelial angiogenesis.

Background: Increased circulating levels of endoglin(+) endothelial microparticles (EMPs) have been identified in several cardiovascular disorders, related to severity. Endoglin is an auxilary receptor for transforming growth factor β (TGF-β) important in the regulation of vascular structure.

Results: We quantified the number of microparticles in plasma of six patients with chronic thromboembolic pulmonary hypertension (CTEPH) and age- and sex-matched pulmonary embolic (PE) and healthy controls and investigated the role of microparticle endoglin in the regulation of pulmonary endothelial function in vitro.

[On the use of photoplasmodynamic method in treatment of suppurative wounds].

A new photoplasmodynamic method and Elektroton-Pulsar hardware system for its implementation are described. The method provides treatment of suppurative wounds by exposure of the infection focus to a gas mixture containing highly active components: O*, O2*, 1O2, O(, O3 traces + UV, etc. The exposure is performed using high-voltage electric discharges interacting with the initial ozone-containing gas mixture.

[A system for implementation of steep massage in patients with musculoskeletal pain syndromes].

A system for implementation of steep massage in patients with musculoskeletal pain syndromes is described. The system provides effective medical care of patients with bearing disorders, scoliosis, osteochondrosis, and other diseases. The system uses steep massage and the effect on the internal receptors of muscles around the backbone.

[Improvement of the information value of multifrequency impedancometry for detection of small tumor arrays].

Use of multifrequency impedancometry makes it possible to considerably increase the information value of electroimpedancometry for malignant tumor diagnosis. Integral characteristics of the tissue electrical impedance vs. frequency curves Z(f) in normal and pathological states are used to obtain additional diagnostic information about the type and physiological state of biological tissues on the basis of calculation of quotients K(P).

[Improvement of organization and economic mechanisms for comprehensive provision of equipment to treatment-and-prophylaxis institutions].

In many domestic treatment-and-prophylaxis institutions, the standard service life of the majority of medical equipment already expired. Further use of this equipment can become hazardous to both patients and medical personnel. Medical techniques implemented in this outdated equipment can also be rather ineffective for diagnosis and treatment planning.

[Use of an apparatus for automatic lung straightening in the management of the pleural cavity in the postoperative period].

An apparatus for automatic lung straightening may be used in medical technologies employed in thoracic (lung) surgery in the postoperative rehabilitation of a patient. This apparatus may automatically (without a physician's or a nurse observance) maintain tension relief in the pleural cavity in the patient on an individual basis, which is required for complete lung strengthening. Its use greatly reduces the number of postoperative complications in the lung, such as residual cavities, edema, and empyema of the pleura.

[Principles in the designing of an impedance electrosurgical apparatus for reliable resection of oncologic tumors and involved biological tissues].

The paper proposes that for more reliable resection of cancer tumors and involved biological tissues during a surgical intervention, the structure of biological tissues should be evaluated by measuring its impedance at two frequencies: 2 and 440 KHz and by calculating the polarization coefficient (Cpolar). Examining Cpolar changes in intact and pathologically altered biological tissues allowed them to be distinguished during a surgical intervention by employing an impedance electrosurgical apparatus.

[Automated system of phasing pulse-wave electrosurgical effects].

The authors propose an automatic system for creating stable hemostasis for an electrosurgical apparatus, which includes a scheme to assess a pulse wave and its maximum and minimum values at the site of surgical exposure, an electrosurgical apparatus, and a scheme to obtain data on the values of the pulse wave in a given patient.

[Evaluation of physical factors of electrosurgical effects as bases in designing automated electrosurgical devices].

The paper shows how to study the physical factors of electrophysical exposure, such as an energetic factor caused by high concentrations of high-frequency current and an electromagnetic factor caused by the presence if an electric field, and other concomitant factors in order to outline ways of designing automatic electrosurgical apparatuses operating more effectively in different lines of surgery.

[Optimization of the impact of electrosurgical devices used in neurosurgery and vascular surgery].

The optimum measuring of power upon electrosurgical exposure is a highly important and pressing problem. Impedance values variable upon exposure are proposed to be used as a measure of the efficiency of exposure. The measured values are compared with the preset ones.

[Development and design of specialized electrosurgical equipment for operations on human organs].

The paper outlines an original circuit of a basic electrosurgical apparatus (ESA) which is equipped with measuring informational transformers for automatic determination of load resistance (R1) and with a continuous memorizing device (CMD). Variants of ESA operating conditions are recorded in the CMD, depending upon the resistance of various particular human tissues. According to R1, one out of 8 areas of loading characteristics stored in the CMD is automatically chosen.