The association between repeat number in C9orf72 and phenotypic variability in Turkish patients with frontotemporal lobar degeneration.

Frontotemporal lobar degeneration (FTLD) describes a group of progressive brain disorders. The expansion of a noncoding GGGGCC (GC) hexanucleotide repeat in the C9orf72 gene is a major cause of both familial FTLD and amyotrophic lateral sclerosis. The aim of this study was to determine the prevalence of C9orf72 GC-repeat expansion in a Turkish population with FTLD and to determine its effects on the phenotype.

Test your memory-Turkish version (TYM-TR): reliability and validity study of a cognitive screening test.

Background/aim: The test your memory (TYM) is reported to be a sensitive cognitive function assessment scale for people with dementia. The aim of the present study was to investigate the reliability and validity of an adapted Turkish version of the TYM (TYM-TR) among Turkish dementia patients.

Materials And Methods: The TYM-TR was given to 59 patients with dementia aged 60+ and 336 normal controls aged 23-75+.