Publications by authors named "Belen Rivera"

Article Synopsis
  • - The study investigated the impact of prolonged cold ischemia times (CIT) and donor age on kidney transplant outcomes for recipients of kidneys from donors after circulatory death (DCD), utilizing a large dataset from 2010-2024.
  • - Analysis of 4092 mate-kidney pairs showed no significant differences in patient death or allograft failure between kidneys with CITs greater than 24 hours and those with shorter CITs.
  • - Prolonged CITs were linked to a higher likelihood of delayed graft function (DGF), suggesting that accepting kidneys with longer CITs should still be considered despite the associated risks.
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Background: The role of steroid maintenance (SM) therapy in older adults with kidney retransplants is uncertain due to the intricate balance between rejection and adverse event risks. We aimed to assess their long-term outcomes, comparing SM versus early steroid withdrawal (ESW).

Methods: Retrospective United Network for Organ Sharing registry cohort study.

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Background: For many surgeons, retirement is an emotionally evocative subject, tied to a sense of loss. With minimal guidelines to facilitate a smooth transition, physicians tend to be inadequately prepared. There are few qualitative studies exploring surgeons' perspectives and none focused on transplant surgeons, a population with arguably unique challenges.

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Video 1Two successful cases of endoscopic treatment for Bouveret syndrome and gallstone ileus are shown, including imaging and endoscopic videos. Endoscopy is favored over surgery due to lower morbidity and mortality rates. Laser lithotripsy offers precision and minimal tissue damage.

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We report the first case of in a dog at Santiago, Chile. From an initial biopsy obtained from the patient, a histopathological study was performed that oriented a fungal infection. The molecular diagnosis from the isolated colony confirmed the identity of the agent.

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Background: This study evaluates the efficacy and safety of robotic-assisted surgical techniques in the treatment of gallbladder cancer, comparing it with traditional open and laparoscopic methods.

Methods: A systematic review of the literature searched for comparative analyses of patient outcomes following robotic, open, and laparoscopic surgeries, focusing on oncological results and perioperative benefits.

Results: Five total studies published between 2019 and 2023 were identified.

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Background: Real-time PCR is the diagnostic technique of choice for the diagnosis and control of equine herpesvirus-1 (EHV-1) in an outbreak setting. The presence of EHV-1 in nasal swabs (NS), whole blood, brain and spinal cord samples has been extensively described; however, there are no reports on the excretion of EHV-1 in urine, its DNA detection patterns, and the role of urine in viral spread during an outbreak.

Objectives: To determine the presence of EHV-1 DNA in urine during natural infection and to compare the DNA detection patterns of EHV-1 in urine, buffy coat (BC) and NS.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the current pandemic disease denominated as Coronavirus Disease 2019 (COVID-19). Several studies suggest that the original source of this virus was a spillover from an animal reservoir and its subsequent adaptation to humans. Of all the different animals affected, cats are one of the most susceptible species.

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Article Synopsis
  • - African swine fever (ASF) is a dangerous disease affecting pigs and wild boar, with recent outbreaks causing significant economic impact due to the absence of effective treatments or vaccines.
  • - An oral vaccine trial for wild boar shows promise, but raises safety concerns, particularly regarding high doses and repeat vaccinations, following the death of one animal during testing.
  • - Despite some issues, low-dose vaccinations resulted in only mild side effects, indicating that this vaccine candidate could be a valuable solution for controlling ASF in wild boar populations, pending further research.
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African swine fever (ASF) is currently the most dangerous disease for the global pig industry, causing huge economic losses, due to the lack of effective vaccine or treatment. Only the early detection of ASF virus (ASFV) and proper biosecurity measures are effective to reduce the viral expansion. One of the most widely recognized risks as regards the introduction ASFV into a country is infected animals and contaminated livestock vehicles.

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The disease produced by the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) is currently one of the primary concerns worldwide. Knowing the zoonotic origin of the disease and that several animal species, including dogs and cats, are susceptible to viral infection, it is critical to assess the relevance of pets in this pandemic. Here, we performed a large-scale study on SARS-CoV-2 serological and viral prevalence in cats and dogs in Spain in order to elucidate their role and susceptibility.

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Article Synopsis
  • Natural SARS-CoV-2 infections in pets have been increasingly reported, particularly among dogs, but their susceptibility is still considered low.
  • A study in Spain found the B.1.1.7 variant of concern in a dog whose owners had COVID-19, showing the dog had high viral loads despite showing no symptoms.
  • This research marks the first detection of the B.1.1.7 variant in a dog in Spain and highlights the need for ongoing monitoring and genetic analysis of infected pets.
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Background: The Culicoides obsoletus species complex (henceforth 'Obsoletus complex') is implicated in the transmission of several arboviruses that can cause severe disease in livestock, such as bluetongue, African horse sickness, epizootic hemorrhagic disease and Schmallenberg disease. Thus, this study aimed to increase our knowledge of the composition and genetic diversity of the Obsoletus complex by partial sequencing of the cytochrome c oxidase I (cox1) gene in poorly studied areas of Spain.

Methods: A study of C.

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Article Synopsis
  • Researchers detected SARS-CoV-2 RNA in 6 out of 71 ferrets in central Spain, indicating possible natural infection.
  • They successfully isolated and sequenced the virus from samples taken from one oral and one rectal swab.
  • The study suggests that ferrets can contract the virus when human transmission rates are high, but small ferret populations likely can't sustain the virus on their own.
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  • Mycobacterium bovis and the Mycobacterium tuberculosis complex are major concerns for wildlife, particularly Eurasian wild boars, due to their role in tuberculosis (TB) spread.
  • A new ELISA test for detecting antibodies in oral fluid samples from TB-infected wild boar showed a strong correlation with traditional serum tests, indicating its effectiveness for TB monitoring.
  • The oral fluid test demonstrated 67.3% sensitivity and 100% specificity, suggesting it could enhance MTC surveillance and control efforts without invasive procedures.
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African swine fever (ASF) is a viral disease of domestic and wild suids for which there is currently no vaccine or treatment available. The recent spread of ASF virus (ASFV) through Europe and Asia is causing enormous economic and animal losses. Unfortunately, the measures taken so far are insufficient and an effective vaccine against ASFV needs to be urgently developed.

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Article Synopsis
  • * In the EU, wild boar are particularly impacted, with ASF spreading due to trade activities and the movement of infected populations, compounded by the absence of an effective vaccine.
  • * A study shows that an orally administered vaccine, derived from a specific ASF virus strain, provided 92% protection in wild boars, marking a significant step towards developing a vaccine for ASF control in wild populations, though further research is needed on its safety and long-term effects.
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In the absence of effective vaccine(s), control of African swine fever caused by African swine fever virus (ASFV) must be based on early, efficient, cost-effective detection and strict control and elimination strategies. For this purpose, we developed an indirect ELISA capable of detecting ASFV antibodies in either serum or oral fluid specimens. The recombinant protein used in the ELISA was selected by comparing the early serum antibody response of ASFV-infected pigs (NHV-p68 isolate) to three major recombinant polypeptides (p30, p54, p72) using a multiplex fluorescent microbead-based immunoassay (FMIA).

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