Identifying patterns to uncover the importance of biological pathways on known drug repurposing scenarios.

Background: Drug repurposing plays a significant role in providing effective treatments for certain diseases faster and more cost-effectively. Successful repurposing cases are mostly supported by a classical paradigm that stems from de novo drug development. This paradigm is based on the "one-drug-one-target-one-disease" idea.

Repositioning Drugs for Rare Diseases Based on Biological Features and Computational Approaches.

Rare diseases are a group of uncommon diseases in the world population. To date, about 7000 rare diseases have been documented. However, most of them do not have a known treatment.