Hypoxia matters: comparison of external and internal training load markers during an 8-week resistance training program in normoxia, normobaric hypoxia and hypobaric hypoxia.

Purpose: To compare external and internal training load markers during resistance training (R) in normoxia (N), intermittent hypobaric hypoxia (HH), and intermittent normobaric hypoxia (NH).

Methods: Thirty-three volunteers were assigned an 8-week R program in either N (690 m, n = 10), HH (2320 m, n = 10), or NH (inspired fraction of oxygen = 15.9%; ~ 2320 m, n = 13).

Effect of a resistance exercise at acute moderate altitude on muscle health biomarkers.

The intensification of the stress response during resistance training (R) under hypoxia conditions could trigger unwanted effects that compromise muscle health and, therefore, the ability of the muscle to adapt to longer training periods. We examined the effect of acute moderate terrestrial hypoxia on metabolic, inflammation, antioxidant capacity and muscle atrophy biomarkers after a single R session in a young male population. Twenty healthy volunteers allocated to the normoxia (N < 700 m asl) or moderate altitude (HH = 2320 m asl) group participated in this study.

Altitude-induced effects on neuromuscular, metabolic and perceptual responses before, during and after a high-intensity resistance training session.

Purpose: We tested if an acute ascending to 2320 m above sea level (asl) affects corticospinal excitability (CSE) and intracortical inhibition (SICI) measured with transcranial magnetic stimulation (TMS) at rest, before, during and after a traditional hypertrophy-oriented resistance training (R) session. We also explored whether blood lactate concentration (BLa), ratings of perceived exertion (RPE), perceived muscular pain and total training volume differed when the R session was performed at hypoxia (H) or normoxia (N).

Methods: Twelve resistance-trained men performed eight sets of 10 repetitions at 70% of one repetition maximum of a bar biceps curl at N (SpO = 98.

Efficacy of resistance training in hypoxia on muscle hypertrophy and strength development: a systematic review with meta-analysis.

A systematic review and meta-analysis was conducted to determine the effects of resistance training under hypoxic conditions (RTH) on muscle hypertrophy and strength development. Searches of PubMed-Medline, Web of Science, Sport Discus and the Cochrane Library were conducted comparing the effect of RTH versus normoxia (RTN) on muscle hypertrophy (cross sectional area (CSA), lean mass and muscle thickness) and strength development [1-repetition maximum (1RM)]. An overall meta-analysis and subanalyses of training load (low, moderate or high), inter-set rest interval (short, moderate or long) and severity of hypoxia (moderate or high) were conducted to explore the effects on RTH outcomes.

Altitude differentially alters the force-velocity relationship after 3 weeks of power-oriented resistance training in elite judokas.

This study investigated the effects of a 3-week power-oriented resistance training programme performed at moderate altitude on the lower-limb maximal theoretical power and force-velocity (F-V) imbalance of elite judokas. Twenty-two elite male judokas were randomly assigned to either a hypobaric hypoxia or normoxia group. Mechanical outputs from an incremental loaded countermovement jump test were assessed at sea level, before and after training, and 1 week later.

Influence of an Acute Exposure to a Moderate Real Altitude on Motoneuron Pool Excitability and Jumping Performance.

The aim of the study was to test whether ascending to a moderate real altitude affects motoneuron pool excitability at rest, as expressed by a change in the H-reflex amplitude, and also to elucidate whether a possible alteration in the motoneuron pool excitability could be reflected in the execution of lower-body concentric explosive (squat jump; SJ) and fast eccentric-concentric (drop jump; DJ) muscle actions. Fifteen participants performed four experimental sessions that consisted of the combination of two real altitude conditions [low altitude (low altitude, 690 m), high altitude (higher altitude, 2,320 m)] and two testing procedures (H-reflex and vertical jumps). Participants were tested on each testing day at 8, 11, 14 and 17 h.

Effects of Resistance Training in Hypobaric vs. Normobaric Hypoxia on Circulating Ions and Hormones.

Hypobaric hypoxia (HH) seems to lead to different responses compared to normobaric hypoxia (NH) during physical conditioning. The aim of the study was to analyze the hormonal and circulating ion responses after performing high-intensity resistance training with different inter-set rest under HH and NH condition. Sixteen male volunteers were randomly divided into two training groups.

Therapeutic approach for digestive system cancers and potential implications of exercise under hypoxia condition: what little is known? a narrative review.

Background: Cancer, like other chronic pathologies, is associated with the presence of hypoxic regions due to the uncontrolled cell growth. Under this pathological hypoxic condition, various molecular signaling pathways are activated to ensure cell survival, such as those that govern angiogenesis, erythropoiesis, among others. These molecular processes are very similar to the physiological response caused by exposure to altitude (natural hypobaric systemic hypoxia), the use of artificial hypoxia devices (systemic normobaric simulated hypoxia) or the delivery of vascular occlusion to the extremities (also called local hypoxia by the blood flow restriction technique).

Neuromuscular Adaptations after an Altitude Training Camp in Elite Judo Athletes.

The aim of this study was to investigate neuromuscular adaptations in elite judo athletes after three weeks of power-oriented strength training at terrestrial altitude (2320 m). Nineteen men were assigned to altitude training (AL) (22.1 ± 2.

Hormonal and Inflammatory Responses to Hypertrophy-Oriented Resistance Training at Acute Moderate Altitude.

This study investigated the effect of a traditional hypertrophy-oriented resistance training (R) session at acute terrestrial hypoxia on inflammatory, hormonal, and the expression of miR-378 responses associated with muscular gains. In a counterbalanced fashion, 13 resistance trained males completed a hypertrophic R session at both moderate-altitude (H; 2320 m asl) and under normoxic conditions (N; <700 m asl). Venous blood samples were taken before and throughout the 30 min post-exercise period for determination of cytokines (IL6, IL10, TNFα), hormones (growth hormone [GH], cortisol [C], testosterone), and miR-378.

Neuromuscular Adaptations in Elite Swimmers During Concurrent Strength and Endurance Training at Low and Moderate Altitudes.

Tomazin, K, Strojnik, V, Feriche, B, Garcia Ramos, A, Štrumbelj, B, and Stirn, I. Neuromuscular adaptations in elite swimmers during concurrent strength and endurance training at low and moderate altitudes. J Strength Cond Res 36(4): 1111-1119, 2022-This study evaluated neuromuscular adaptations in elite swimmers during concurrent strength and endurance training (SET) at low (295 m) and moderate (2,320 m) altitudes.

Altitude-induced effects on muscular metabolic stress and hypertrophy-related factors after a resistance training session.

This study examined the acute effects of exposure to moderate altitude on factors associated with muscular adaptations following whole-body hypertrophy-oriented resistance training ( ) sessions. Thirteen resistance-trained males completed both counterbalanced standard hypertrophic sessions (3 sets × 10RM, 2 min rest) at moderate-altitude (H; 2320 m asl) and under normoxic conditions (N; <700 m asl). Participants rested 72 h between training sessions.

Mean Propulsive Velocity Is a Viable Method for Adjusting the Resistance-Training Load at Moderate Altitude.

We examined the viability of using mean propulsive velocity (MPV) to adjust the load in the countermovement jump (CMJ) at moderate altitude. Twenty-four volunteers were assigned to a 4-week power-oriented resistance training (R) program in either normoxia (N, 690 m) or intermittent hypobaric hypoxia (IH, 2,320 m). The load was adjusted to maintain execution velocity of CMJ at 1m·s of MPV.

Force-Velocity Relationship in the Countermovement Jump Exercise Assessed by Different Measurement Methods.

This study aimed to compare force, velocity, and power output collected under different loads, as well as the force-velocity (F-V) relationship between three measurement methods. Thirteen male judokas were tested under four loading conditions (20, 40, 60, and 80 kg) in the countermovement jump (CMJ) exercise, while mechanical output data were collected by three measurement methods: the Samozino's method (SAM), a force platform (FP), and a linear velocity transducer (LVT). The variables of the linear F-V relationship (maximum force [F0], maximum velocity [V0], F-V slope, and maximum power [P0]) were determined.

Effect of acute exposure to moderate altitude on kinematic variables of the ippon-seoi-nage and its relationship with the countermovement jump in elite judokas.

This study aimed to assess the effect of acute exposure to moderate altitude on kinematic variables of the ippon-seoi-nage and on the mechanical outputs of the countermovement jump (CMJ). Thirteen elite male judokas from the Spanish Judo Training Centre in Valencia (age: 21.54 ± 2.

Associations of the Force-velocity Profile with Isometric Strength and Neuromuscular Factors.

We aimed to explore relationships between the force-velocity (FV) profile and the isometric muscle torque performance during a knee extension task. The FV profile (force-intercept [F], velocity-intercept [V], maximum power [P], and FV slope) during the countermovement jump (CMJ) exercise and isometric maximum voluntary torque (MVIC) and explosive voluntary torque production were assessed in 43 participants. Electromyography (EMG) was recorded during the isometric assessments and resting muscle architecture measurements were also performed (quadriceps thickness, vastus lateralis pennation angle and fascicle length).

Muscle Activation During Power-Oriented Resistance Training: Continuous vs. Cluster Set Configurations.

Morales-Artacho, AJ, García-Ramos, A, Pérez-Castilla, A, Padial, P, Gomez, AM, Peinado, AM, Pérez-Córdoba, JL, and Feriche, B. Muscle activation during power-oriented resistance training: continuous vs. cluster set configurations.

Intermittent Resistance Training at Moderate Altitude: Effects on the Force-Velocity Relationship, Isometric Strength and Muscle Architecture.

Intermittent hypoxic resistance training (IHRT) may help to maximize the adaptations following resistance training, although conflicting evidence is available. The aim of this study was to explore the influence of moderate altitude on the functional, neural and muscle architecture responses of the quadriceps muscles following a power-oriented IHRT intervention. Twenty-four active males completed two 4-week consecutive training blocks comprising general strengthening exercises (weeks 1-4) and power-oriented resistance training (weeks 5-8).

Oxidative stress in elite athletes training at moderate altitude and at sea level.

Using a controlled parallel group longitudinal trial design, we investigated the effects of different training interventions on the prooxidant/antioxidant status of elite athletes: living and training at moderate altitude for 3 (Hi-Hi3) and 4 weeks (Hi-Hi), and for 4 weeks too, living high and training high and low (Hi-HiLo) and living and training at sea level (Lo-Lo). From 61 swimmers, 54 completed the study. Nitrites, carbonyls, and lipid peroxidation (LPO) levels were assessed in plasma.

Influence of a Cluster Set Configuration on the Adaptations to Short-Term Power Training.

Morales-Artacho, AJ, Padial, P, García-Ramos, A, Pérez-Castilla, A, and Feriche, B. Influence of a cluster set configuration on the adaptations to short-term power training. J Strength Cond Res 32(4): 930-937, 2018-This study investigated the effects of a traditional (TT) vs.