The effect of continuous positive airway pressure on middle ear pressure.

Objectives/hypothesis: To investigate the effect of continuous positive airway pressure (CPAP) on middle ear pressure in patients with obstructive sleep apnea syndrome (OSAS).

Study Design: Prospective clinical case-control study.

Methods: Seventy-eight patients with moderate and severe OSAS (the mean apnea-hypopnea indexes were 22.