Publications by authors named "Bejjanki Kavya Madhuri"

Article Synopsis
  • The study aimed to analyze high-risk histopathological features in eyes with retinoblastoma (RB) after enucleation and compare patient outcomes globally.
  • A total of 1,426 RB cases were reviewed, revealing significant differences in histopathological features across continents, with Asia showing the highest rates of massive choroidal invasion and optic nerve invasion.
  • The findings indicated that patients from South America and Asia faced greater risks of tumor recurrence, systemic metastasis, and mortality compared to those from Australia, Europe, and North America.
View Article and Find Full Text PDF

Objective: To study the efficacy and side-effect profile of topical 5-Fluorouracil (5-FU) in the treatment of ocular surface squamous neoplasia (OSSN).

Methods: Retrospective study of 101 eyes of 100 patients treated with 5-FU with one week on and 3 weeks off regimen.

Results: Of the 100 patients (101 eyes), the mean age at diagnosis of OSSN was 49 (median, 52 years; range, 11-87 years).

View Article and Find Full Text PDF

Purpose: To describe the clinical features, histopathology, treatment, and outcomes of patients with ocular surface squamous neoplasia (OSSN) presenting to a referral centre in India.

Methods: Retrospective interventional study.

Results: Of 438 patients, the mean age at presentation was 49 years.

View Article and Find Full Text PDF

Objectives: To study the efficacy and the long-term outcomes of treating micro and macrocystic orbital and/or adnexal lymphatic malformations (OA-LM) with protocol-based bleomycin sclerotherapy.

Methods: A retrospective interventional study of 69 eyes having OA-LM treated with non-image guided transcutaneous or transconjunctival bleomycin sclerotherapy (1IU/ml aqueous solution) between December 2014 and December 2018. Based on clinical regression, the outcomes were classified as excellent, good, fair and poor.

View Article and Find Full Text PDF

Purpose: The aim of the study was to investigate the clinical resolution versus radiologic regression of orbital lymphatic malformations (LMs) following treatment with intralesional bleomycin sulfate sclerotherapy.

Methods: A retrospective interventional study of 24 eyes with orbital LMs treated with nonimage-guided bleomycin sclerotherapy. The clinical and radiologic outcomes were classified as excellent, good, fair, and poor.

View Article and Find Full Text PDF

Purpose: To describe a case series of periocular lobular capillary hemangiomas in adults, outlining characteristic clinical and histopathological patterns.

Materials And Methods: This was a retrospective case series of 16 patients with review of clinical and histopathological features.

Results: Eleven male and five female patients were diagnosed with periocular lobular capillary hemangioma at a median age of 38 years (mean, 41 years; range, 21-71 years).

View Article and Find Full Text PDF

Purpose: To study the factors influencing the response to treatment with interferon alfa 2b (IFN) in ocular surface squamous neoplasia (OSSN)Methods: Retrospective study of 91 patientsResults: The mean age at presentation of patients with OSSN was 58 years (median, 60 years; range, 21 to 83 years). The mean number of clock hours of conjunctiva/cornea/limbus involvement by the tumor was 6 (median, 6; range, 1 to 12). The mean duration of topical IFN was 3 months (median, 3 months; range, 1 to 6 months) and the mean number of subconjunctival injections of IFN was 2 (median, 2; range, 0 to 6), till complete tumor regression or initiation of alternate treatment.

View Article and Find Full Text PDF

Myofibroma is a rare benign mesenchymal tumor of uncertain histogenesis. A six-year-old boy presented with a unilateral lower eyelid mass of six weeks' duration. MRI revealed a circumscribed mass in the inferolateral orbit with bony erosion.

View Article and Find Full Text PDF

Purpose: To study the proportion of eyelid malignant tumors in an Asian Indian population and to review their clinical features and outcomes.

Methods: This is a retrospective study of 536 patients.

Results: The mean age at presentation with eyelid malignancy was 58 years.

View Article and Find Full Text PDF

Objective: To review the indications of enucleation in Asian Indian patients and study the trend over the 22-year period.

Methods: Retrospective study of 2009 patients who underwent enucleation.

Results: The mean age at presentation of patients who underwent enucleation was 155 months The histopathology diagnosis included a benign tumor (n = 22, 1%), malignant tumor (n = 1472, 73%), acute trauma (n = 93, 5%), retinal vascular disease (n = 50, 3%), inflammatory/infective pathology (n = 33, 2%), or other miscellaneous/non-specific diagnosis (n = 460, 23%).

View Article and Find Full Text PDF