Temporal trends in disability adjusted life year and mortality for colorectal cancer attributable to a high red meat diet in China from 1990 to 2021: an analysis of the global burden of disease study 2021.

Background: High red meat consumption is a main modifiable risk factor for colorectal cancer mortality (CRC), but its attributable disease burden remains unclear in China. We aimed to analyze the temporal trends in CRC deaths and disability-adjusted life years (DALYs) attributable to high red meat consumption in China from 1990 to 2021 and to predict the disease burden in the next 15 years.

Methods: Data was obtained from the Global Burden of Disease (GBD) 2021 study.

Comparative enantioseparation of seven triazole fungicides on (S,S)-Whelk O1 and four different cellulose derivative columns.

The comparative enantioseparation of seven chiral triazole fungicides on a Pirkle type (S,S)-Whelk O1 chiral column and four different cellulose derivative columns, namely cellulose tribenzoate (CTB), cellulose tris(4-methylbenzoate) (CTMB), cellulose triphenylcarbamate (CTPC), and cellulose tris(3,5-dimethylphenyl carbamate) (CDMPC), in normal phase mode is described. The seven triazole fungicides investigated were tebuconazole, hexaconazole, myclobutanil, diniconazole, uniconazole, paclobutrazol, and triadimenol. The chiral separation of each solute was investigated with ethanol, n-propanol, iso-propanol, and n-butanol, respectively, as polar modifier in the hexane mobile phase.

Effect of the mobile phase on the retention behavior of optical isomers of the mandelic acid derivative methyl 2-phenyl-2-(tetrahydropyranyloxy) acetate by chiral HPLC.

Conditions for separation of enantiomers of a mandelic acid derivative, methyl 2-phenyl-2-(tetrahydropyranyloxy) acetate (the analyte) were studied. Because of the presence of two chiral carbons, the analyte consists of four stereoisomers stable at ambient temperature. Chiral HPLC of the analyte resulted in four peaks, using an (S,S)-Whelk-O1 column with the mobile phase consisting of hexane and the t-butyl methyl ether (TBME).