Publications by authors named "Beiang Zhang"

Article Synopsis
  • - The study focuses on the N-protomer of 4-aminobenzoic acid, investigating the gas-phase chemistry of the 4-(carboxyphenyl)trimethylammonium ion formed through electrospray ionization (ESI).
  • - Researchers synthesized and purified the compound, conducting experiments using mass spectrometry to observe fragmentation patterns, primarily involving the loss of methyl radicals.
  • - Findings indicate that the free carboxylic acid group in the compound shows low reactivity towards various neutral reagents, aligning with theoretical calculations that suggest specific reaction mechanisms.
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Zika virus (ZIKV) infection arises as a global health threat owing to its association with Guillain-Barre syndrome and microcephaly in adults and fetuses since the most recent epidemics. Although extraordinary efforts have been underway globally to identify safe and effective treatments for ZIKV, therapeutic progressions seem to remain stagnant, especially for treating congenital ZIKV infection. Bio-compounds from medicinal plants evolutionarily optimized as drug-like molecules offer eligible sources of pharmaceuticals and lead drugs to fight against viral infections.

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Increasing evidence has shown that AGEs can impair insulin sensitivity and affect glucose homeostasis. Owing to the heterogeneity of AGEs, it is still unclear which one has the strongest potential to disrupt glucose metabolism. Our study explored the effects of different types of AGEs on hepatic glucose metabolism.

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