Publications by authors named "Bei-Zhan Jiang"

Article Synopsis
  • This study investigates how DKK1 affects the behavior of human dental pulp cells when exposed to lipopolysaccharide (LPS), focusing on cell migration, proliferation, and differentiation.
  • DKK1 was found to enhance the migration and differentiation of these cells, while it did not significantly impact their proliferation in the presence of LPS.
  • The findings suggest that the effects of DKK1 may be linked to its inhibition of the Wnt/β-catenin signaling pathway.
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Malocclusion is one of the three most common oral diseases reported by World Health Organization(WHO). In China, its incidence rate is rising. Malocclusion seriously affects the dental and maxillofacial function, facial appearance and growth development of nearly 260 million children in China, and what is more, it affects their physical and mental health development.

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Objective: Versican is a large, aggregating chondroitin sulphate proteoglycan. In dental tissue, versican expression occurs primarily in mesenchymal tissue but rarely in epithelial tissue. We investigated the expression, localisation and synthesis of versican in the enamel organ of the developing tooth germ.

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