Publications by authors named "Bei-Shi Zheng"

Article Synopsis
  • Pancreatic cancer is a leading cause of cancer deaths and is linked to mutations in the DMKN-β gene.
  • The study investigates the role of the DMKN-α gene in pancreatic cancer by analyzing gene expression and conducting various tests on cancerous and normal pancreatic cells.
  • Results show that overexpression of DMKN-α promotes tumor growth, migration, and invasion, indicating it may function as an oncogene in pancreatic cancer.
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Aim: Post-operative fatigue syndrome (POFS) is a common complication that prolongs the recovery to normal function and activity after surgery. The aim of the present study was to explore the mechanism of central fatigue in POFS and the anti-fatigue effect of ginsenoside Rb1.

Method: We investigated the association between inflammation, indoleamine 2,3-dioxygenase (IDO) enzyme, and tryptophan metabolism in the hippocampus of POFS rats.

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Article Synopsis
  • * Four groups of rats were used: a control group, and three trauma groups (intestinal manipulation, ischemia/reperfusion injury, and peritoneal air exposure), with gastrointestinal transit and various biochemical markers analyzed after surgery.
  • * Results showed that intestinal manipulation and air exposure led to similar gastrointestinal motility impairment, while ischemia/reperfusion had less impact; however, all types of trauma can lead to POI, suggesting oxidative stress plays a significant role alongside inflammation.
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Background: Laparoscopic surgery and enhanced recovery after surgery (ERAS) programs were two major improvements for the management of colorectal diseases. The purpose of this systemic review was to examine whether laparoscopic colorectal surgery still improved short-term postoperative outcomes in comparison with open surgery when both groups of patients received ERAS programs.

Methods: PubMed, Embase, the Cochrane Central Register of Controlled Trials, and reference lists of the identified studies were searched to identify randomized clinical trials that compared laparoscopic with open surgery in patients undergoing colorectal resection in the context of ERAS programs.

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