Zhonghua Jie He He Hu Xi Za Zhi
May 2012
Objective: To investigate the effects of H(2) Relaxin (Relaxin) on airway remodeling and the expression of cyclin D(1) in a murine model of chronic asthma.
Methods: Forty BALB/c mice were randomly divided into 4 groups:a normal control group, an asthma group, a vehicle control group and a relaxin treatment group, with 10 mice in each. The mice were sensitized and challenged with ovalbumin (OVA) to establish the chronic asthmatic model.
Gold-catalyzed reactions, which have been widely explored over the past several years, are powerful tools in organic synthesis to access complex molecular frameworks, and some corresponding excellent reviews have been reported. However, little attention has been paid to summarize the reactions of strained small-ring-containing molecules catalyzed by gold. This critical review mainly puts its emphasis on the recent progress in the field of gold-catalyzed transformations of cyclopropyl-, cyclopropenyl-, epoxy- and aziridinyl-containing molecules.
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