Publications by authors named "Behzad Emadi"
Transfusion transmissible infections (TTIs) have been a public health challenge for the accessibility, quality and safety of blood transfusion. The present study aimed to consider the prevalence and the trends of hepatitis B virus (HBV), hepatitis C virus (HCV), Human T-cell leukemia virus type 1 (HTLV-1), human immunodeficiency virus (HIV) and syphilis across the ten years among retrospective blood donors. A retrospective investigation of blood donors' data covering the period from 22 May 2009 to 22 May 2019 was done.
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- A study was conducted to assess the frequency of Extended-Spectrum Beta-Lactamase (ESBL) genes in strains from nosocomial infections to understand their role in antibiotic resistance.
- Out of 100 bacterial strains analyzed, 59% were identified as ESBL positive, but the study did not find two specific ESBL genes; however, another gene was present in 42% of the strains.
- The findings indicate a high prevalence of antibiotic-resistant strains in Iran, emphasizing the urgent need for infection control measures in healthcare settings to combat the spread of these resistant infections.
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- Helicobacter pylori (Hp) is linked to peptic ulcers, chronic gastritis, and gastric cancer, with certain pathogenicity genes contributing to more severe infection outcomes.
- The study, conducted on patients at Shariati Hospital in Tehran, involved collecting gastric biopsy specimens from January to November 2015 to isolate and analyze Hp strains for specific virulence genes.
- The results showed a 65.7% isolation rate of Hp strains, with notable differences in the presence of certain genes between patients with peptic ulcer disease (PUD) and gastric cancer (GC).
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- The study investigated the prevalence and virulence factors of Listeria monocytogenes using multiplex polymerase chain reaction (MPCR) on various samples.
- A total of 617 samples were analyzed, with L. monocytogenes found in 46 of them (7.45%); the virulence genes inlA, inlC, and inlJ were detected at rates of 100%, 76.26%, and 71%, respectively.
- The findings support the effectiveness of MPCR in quickly identifying L. monocytogenes and confirm the significance of the detected genes in the bacteria's pathogenicity.
Background: Sigma factors are proteins that regulate transcription in bacteria. Sigma factors can be activated in response to different environmental conditions. The rpoS (RNA polymerase, sigma S) gene encodes sigma-38 (σ38, or RpoS), a 37.
View Article and Find Full Text PDFBackground: Chemotherapy plays a very important role in the treatment of leukemia but the resistance properties of the lymphoblasts limit the effect of chemotherapy. One of the main mechanisms of resistance to chemotherapy is the increased expression of MDR1 gene. The aim of this study was to explore the effect of resveratrol on the expression of MDR1 gene in leukemic lymphoblast of new cases of acute lymphoblastic leukemia (ALL) patients in vitro.
View Article and Find Full Text PDFBackground: Resistance to antimicrobial agents among Staphylococcus aureus is an increasing problem. Two common genes responsible for resistance to macrolide, lincosamide and streptogramin B (MLSB) antibiotics are the ermA and ermC genes. Three resistance phenotypes have been detected to these antibiotics: strains containing cMLSB (constitutive MLSB) and iMLSB (inducible MLSB), which are resistant to macrolide, lincosamide and streptogramin B antibiotics, and MS, which is only resistant to macrolide and streptogramin B antibiotics.
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