Noninvasive characterization of oocyte deformability in microconstrictions.

Oocytes naturally present mechanical defects that hinder their development after fertilization. Thus, in the context of assisted reproduction, oocyte selection based on their mechanical properties has great potential to improve the quality of the resulting embryos and the success rate of these procedures. However, using mechanical properties as a quantifiable selective criterion requires robust and nondestructive measurement tools.

On-chip dielectrophoretic device for cancer cell manipulation: A numerical and artificial neural network study.

Breast cancer, as one of the most frequent types of cancer in women, imposes large financial and human losses annually. MCF-7, a well-known cell line isolated from the breast tissue of cancer patients, is usually used in breast cancer research. Microfluidics is a newly established technique that provides many benefits, such as sample volume reduction, high-resolution operations, and multiple parallel analyses for various cell studies.

Numerical simulation of critical particle size in asymmetrical deterministic lateral displacement.

Microfluidics devices are widely used for particle separation. Deterministic Lateral Displacement (DLD) is a passive method for particle separation. DLD devices mainly separate particles based on their sizes.