Fluorescence switchable sensor enabled by a calix[4]arene-Cu(II) complex system for selective determination of itraconazole in human serum and aqueous solution.

A switchable fluorescence sensor based on a calix (Monapathi et al., 2021) [4]arene:Cu complex (FLCX/Cu) has been developed for the detection of itraconazole (ITZ) with high sensitivity and specificity. For the development of the sensor, the selective complexation of a fluorescent calix (Monapathi et al.

Nano-scale selective and sensitive optical sensor for metronidazole based on fluorescence quenching: 1H-Phenanthro[9,10-d]imidazolyl-calix[4]arene fluorescent probe.

It is crucial to determine and control the metronidazole (MET) ingredient in food and pharmaceuticals for human health and food safety. Even though many sensors have been previously reported to detect MET, there is still a need for a highly selective and sensitive, easy, fast, cost-effective sensor in this area. Herein, we report a fluorescent calix[4]arene derivative (PIMC) for highly selective and sensitive and facile and rapid MET detection based on fluorescence (FL) quenching.

Rapid and real-time detection of arginine enantiomers by QCM sensor having a Calix[4]arene receptor bearing asymmetric centers.

This paper describes the sensing studies of a chiral calix[4]arene receptor (5) having (R)-2-phenylglycinol moiety for arginine enantiomers (D-/L-arginine) by using Quartz Crystal Microbalance (QCM) technique. The initial experiments have revealed that the chiral calix[4]arene 5 coated QCM (CCC-QCM) sensor showed good sensing for arginine enantiomers, such that it has exhibited higher sensing towards D-arginine than that of L-arginine. It has been determined that the sensitivity, limit of detection values of CCC-QCM sensor for the D-/L-arginine solutions as 0.

A phenyl glycinol appended calix[4]arene film for chiral detection of ascorbic acid on gold surface.

This paper describes the synthesis of new chiral calix [4]arene derivative having (R)-2-phenylglycinol moiety (compound 6), and its chiral recognition studies for ascorbic acid (AA) enantiomers by using Quartz Crystal Microbalance (QCM). Initial experiments indicated that the outstanding selective chiral recognition (α) was observed as 2.61 for l-enantiomer of AA.

Fast and Reversible "Turn on" Fluorescent Sensors Based on Bisphenol-a for Zn in Aqueous Solution.

Two novel bisphenol-A derivatives (R1 and R2) linked pyrene and napthylthiazole moieties were synthesized via condensation reaction, and positively applied for the selective recognition of Zn ion in EtOH/HO. Their optical properties were observed by using UV-vis and fluorescence measurements. R1 and R2 exhibited high selectivity and sensitivity towards Zn over other metal ions.

Selective chiral recognition of alanine enantiomers by chiral calix[4]arene coated quartz crystal microbalance sensors.

We describe the synthesis of new chiral calix[4]arene derivatives having (R)-1-phenylethylamine, (S)-1-phenylethylamine, (R)-2-phenylglycinol, and (S)-2-phenylglycinol moieties, and chiral recognition studies for enantiomers of some selected α-amino acid derivatives such as alanine, phenylalanine, serine, and tryptophan using a quartz crystal microbalance (QCM). Initial experiments indicated that the highest selective chiral recognition factor was 1.42 for alanine enantiomers.

Selective and Sensitive Fluorescein-Benzothiazole Based Fluorescent Sensor for Zn Ion in Aqueous Media.

An efficient fluorescent sensor based on fluorescein-benzothiazole (FB) for Zn ion was synthesized and characterized systematically. FB exhibited selective and sensitive recognition toward Zn in MeCN-HO (v/v = 2/1) over other cations due to the spirolactam ring-opening power of Zn. The complexation property of FB with Zn ion was examined by H NMR, C NMR and FTIR experiments.

4-tert-butylcalix[4]arene having nitrile pendant groups as Hg²⁺ selective receptors.

We synthesized a series of 4-tert-butylcalix[4]arene nitriles (5-7) by the reaction of 4-tert-butylcalix[4]arene (1) with 4'-(6-bromohexyloxy)biphenyl-4-carbonitrile (2), 4'-(10-bromode-cyloxy)biphenyl-4-carbonitrile (3), and 4'-(12-bromododecyloxy)biphenyl-4-carbonitrile (4) and characterized their structures, respectively. The extraction abilities of newly synthesized 5-7 toward some selected heavy metal cations, such as Co(2+), Cu(2+), Ni(2+), Zn(2+), Cd(2+), and Hg(2+), were first evaluated and compared by the solvent extraction method. The extraction results revealed that 5-7 were efficient and selective cation receptors for Hg(2+) over-selected cations.