Effect of prunes on gastrointestinal function after benign gynecological surgery: a randomized control trial.

Objective: To investigate the effect of postoperative prune consumption on time to first bowel movement after benign gynecologic surgery.

Materials And Methods: In this randomized, open label, controlled trial, 77 adult women who had benign gynecologic surgery that required at least one night in the hospital were enrolled from July 2018 to April 2019. Participants were randomized in a 1:1 ratio to one of two groups using a randomization assignment: 4 oz prunes daily plus docusate sodium 100 g twice daily versus docusate alone.

Lavender Aromatherapy for Anxiety and Pain During Multichannel Urodynamics: A Randomized Controlled Pilot Trial.

Objective: Our objective was to determine if there is a difference in anxiety during urodynamics in women given lavender aromatherapy (lavender) versus placebo.

Methods: This was a randomized, controlled trial of women scheduled for urodynamic testing with baseline anxiety. Participants rated their anxiety and pain immediately before the examination and then were randomized to lavender or placebo.

Translation and linguistic validation of the Female Genitourinary Pain Index in Spanish.

Introduction And Hypothesis: We sought to develop a Spanish translation of the Female Genitourinary Pain Index (GUPI) and to validate this instrument in US Latina women.

Methods: Translation back-translation was performed to create the initial Spanish version. Bilingual women with pelvic and/or genitourinary pain were recruited from clinical sites and social media.

Route-specific association of progestin therapy and concurrent metformin use in obese women with complex atypical hyperplasia.

Introduction: Previous studies have suggested that metformin use may enhance the therapeutic effect of progestin therapy for endometrial hyperplasia or malignancy. However, it is not known how the impact of concurrent metformin may be altered by route of progestin therapy, either locally via an intrauterine device or systemically. This study examined the effectiveness of concurrent metformin use and progestin therapy for women with complex atypical hyperplasia stratified by progestin route (systemic vs local).

Does Obtaining a Diagnosis of Interstitial Cystitis/Bladder Pain Syndrome Improve Symptoms or Quality of Life? A Cross-sectional Questionnaire-Based Study.

Objectives: The aim of this study was to investigate whether receiving a clinical diagnosis of interstitial cystitis (IC) or bladder pain syndrome (BPS) improves patients' symptoms, health-related quality of life (HRQOL), or ability to cope with their symptoms.

Methods: In this cross-sectional study, participants with self-reported IC/BPS completed an online questionnaire recalling their perceived change in symptoms after diagnosis and treatment. The questionnaire included demographic information, overall HRQOL measured on a visual analog scale (VAS), O'Leary-Sant Interstitial Cystitis Problem Index, the Urinary Impact Questionnaire, and questions regarding patient beliefs about diagnosis.

Progestin therapy for obese women with complex atypical hyperplasia: levonorgestrel-releasing intrauterine device vs systemic therapy.

Background: Though hysterectomy remains the standard treatment for complex atypical hyperplasia, patients who desire fertility or who are poor surgical candidates may opt for progestin therapy. However, the effectiveness of the levonorgestrel-releasing intrauterine device compared to systemic therapy in the treatment of complex atypical hyperplasia has not been well studied.

Objective: We sought to examine differences in treatment response between local progestin therapy with the levonorgestrel-releasing intrauterine device and systemic progestin therapy in women with complex atypical hyperplasia.

Effectiveness of progestin-based therapy for morbidly obese women with complex atypical hyperplasia.

Objective: While progestins can effectively treat women with complex atypical hyperplasia (CAH), the impact of body habitus on treatment outcome is not well studied. We examine the association between body mass index (BMI) and progestin treatment outcomes.

Methods: We conducted a retrospective cohort study of patients diagnosed with hyperplasia between 2003 and 2011.

Vaginal Angiomyofibroblastoma: A Case Report and Review of Diagnostic Imaging.

Background: Angiomyofibroblastoma (AMFB) is a benign mesenchymal tumor most commonly found in the female genital tract of premenopausal women. Although rare, AMFB is an important consideration in the differential diagnosis of vulvar and vaginal masses, as it must be distinguished from aggressive angiomyxoma (AA), a locally recurrent, invasive, and damaging tumor with similar clinical and pathologic findings.

Case: We describe a patient with a 4 cm vaginal AMFB and the relevant preoperative radiographic imaging findings.

Randomized controlled trial of 2% lidocaine gel versus water-based lubricant for multi-channel urodynamics.

Introduction And Hypothesis: The purpose of the study was to determine if there is a difference in pain during and after multichannel urodynamic testing in women when using 2% lidocaine gel versus water-based lubricant.

Methods: This was a randomized, controlled, double-blinded study. Women scheduled to undergo urodynamic testing were invited to participate.

Effect of pessary use on hydronephrosis in women with advanced pelvic organ prolapse: a self-selected interventional trial.

Introduction And Hypothesis: The purpose of this study was to determine the proportion of women who demonstrate improvement in hydronephrosis after pessary placement for advanced pelvic organ prolapse (POP).

Methods: This was a planned subset analysis of a prospective study on the prevalence of hydronephrosis in women with advanced POP. Women with anterior or apical POP ≥1 cm past the hymenal remnant were enrolled and screened for hydronephrosis.

Prevalence of Hydronephrosis in Women With Advanced Pelvic Organ Prolapse.

Objective: To describe the prevalence of hydronephrosis in advanced pelvic organ prolapse (POP) and to describe clinical and urodynamic parameters associated with hydronephrosis.

Materials And Methods: Prospective, observational cohort study examining the prevalence of hydronephrosis in advanced POP. Women with a POP-Q examination of at least +1 for points C, Aa, or Ba were enrolled and screened for hydronephrosis.

Comparison of 2 simulation models for teaching obstetric anal sphincter repair.

Objective: The purpose of this study was to compare the utility of 2 surgical models for obstetric anal sphincter repair for improving resident knowledge, confidence level, and repair technique.

Study Design: Third- and fourth-year obstetrics and gynecology residents at LAC + USC Medical Center performed simulated anal sphincter repair on both sponge and beef tongue surgical models. Resident knowledge, confidence, technical skill, and preference were assessed after each model was performed.

Bladder wall hamartoma: an unusual cause of urinary urgency and frequency.

We present a case of a 51-year-old woman with urinary urgency, frequency, and lower abdominal pain; she was found to have an anterior vaginal wall mass on examination. Ultrasound and computerized tomography revealed a complex solid cystic mass. Transvaginal partial cystectomy was performed; histologic examination revealed hamartoma of the urinary bladder.

Comparison of the POP-Q examination, transvaginal ultrasound, and direct anatomic measurement of cervical length.

Introduction And Hypothesis: Our objective was to determine the relationship between the Pelvic Organ Prolapse Quantification (POP-Q) examination for determining cervical length (CL) and CL at hysterectomy. Secondary objectives were to define cervical elongation using both measures in a urogynecologic population, determine the relationship between POP-Q estimate and CL on ultrasound (US) and examine the interobserver reliability of each mode of measurement.

Methods: This was a prospective cohort study of women scheduled for hysterectomy at the Los Angeles County + University of Southern California (LAC + USC) medical center.

The relationship between uterine leiomyomata and pelvic floor symptoms.

Introduction And Hypothesis: To compare pelvic floor symptoms in women with a leiomyomatous uterus ≤12 weeks and those >12 weeks in size and to evaluate the resolution of these symptoms after surgical intervention.

Methods: The PFDI-20, PFIQ-7 and 3-day voiding diaries were administered prospectively to all subjects. Demographics and questionnaire responses were compared using a t test, Chi-squared test or Mann-Whitney U test as indicated.

The multicenter urogynecology study on education: associations between educational outcomes and clerkship center characteristics.

Objective: : The objective of the study was to examine the effect of center characteristics on educational experiences and female pelvic medicine knowledge changes in third-year students at 6 medical schools.

Methods: : In this secondary analysis of data acquired during a prospective, multicenter study conducted from May 2008 through June 2009, preclerkship and postclerkship third-year medical students scored their knowledge of 12 female pelvic medicine topics and 4 office procedures (knowledge scores [KSs]). Postclerkship, students also reported the number and type of learning experiences they had encountered.

Multicenter Urogynecology Study on Education: Medical Student Educational Experiences and Knowledge Outcomes During the OBGYN Clerkship.

Objective: : The objective of this study was to describe self-assessed student knowledge of female pelvic medicine (FPM) during the OBGYN clerkship.

Methods: : Students at 6 sites scored their knowledge of 12 FPM topics and 4 procedures both before and after their clerkship. Analysis included Wilcoxon tests, Spearman correlation, and univariate and multivariate models.

Randomized trial of estradiol vaginal ring versus oral oxybutynin for the treatment of overactive bladder.

Objective: The aim of this study was to compare the efficacy of the ultralow-dose estradiol vaginal ring with that of oral oxybutynin in the treatment of overactive bladder in postmenopausal women.

Methods: Postmenopausal women with an overactive bladder were recruited from the general gynecology clinic. Participants were randomized to receive either the ultralow-dose estradiol vaginal ring or oral oxybutynin for 12 weeks.

Is there a pelvic organ prolapse threshold that predicts bladder outflow obstruction?

Introduction And Hypothesis: To determine if there is a cutpoint of anterior vaginal wall prolapse which predicts bladder outflow obstruction.

Methods: Subjects with and without bladder outflow obstruction (BOO) were identified. Baseline characteristics, urodynamics, and exam findings were compared.

Colorectal and anal symptoms in women with urinary incontinence and pelvic organ prolapse.

Introduction And Hypothesis: Our aim was to determine the prevalence of colorectal and anal (CRA) symptoms in women with urinary incontinence and pelvic organ prolapse (UI/POP) in a predominantly Latina population.

Methods: We reviewed charts of women seen in the urogynecology clinic for UI/POP for those who completed the colorectal anal distress inventory-8 (CRADI-8) on their first visit. A detailed history was taken independent of the questionnaire.

Actinomyces infection associated with the transobturator sling.

We present a case of Actinomyces infection associated with the transobturator sling. The patient had a transobturator sling complicated only by a left vaginal sulcal perforation. She subsequently developed mesh erosion that led to two partial mesh resections performed in the operating room at 6 weeks and again at 6 months after the initial surgery.

Does mental imagery prior to cystoscopy make a difference? A randomized controlled trial.

Objective: We sought to determine whether mental imagery improves surgical performance of residents novice to cystoscopy.

Study Design: We performed a multicenter randomized controlled trial. Residents who had performed < or = 3 cystoscopies were randomized to preoperative mental imagery sessions or reading a book chapter describing cystoscopy.

Effectiveness of transobturator tape in women with decreased urethral mobility.

Objective: To determine whether preoperative urethral mobility is associated with success of the transobturator insertion of suburethral polypropylene slings.

Study Design: A cohort of women who underwent a transobturator insertion of a suburethral polypropylene sling for urodynamic stress incontinence between October 2003 and January 2005 was prospectively assessed.

Results: Of the 134 women in the study cohort, 107 (80%) provided postoperative data at a median followup interval of 10 months.

The effect of transdermal and vaginal estrogen therapy on markers of postmenopausal estrogen status.

Objective: To compare serum 17beta-estradiol (E2), estrone (E1), estrone sulfate, follicle-stimulating hormone, luteinizing hormone, sex hormone-binding globulin, vaginal pH, and the vaginal maturation indices in women using a low-dose transdermal patch releasing 14 microg of E2 per day and a vaginal ring releasing 7.5 microg of E2 per day.

Design: Twenty-four postmenopausal women were randomly assigned to either the patch (n = 12) or the ring (n = 12) for a 12-week study period.

Decreased rate of obstetrical anal sphincter laceration is associated with change in obstetric practice.

A study was conducted to describe the rate of obstetrical anal sphincter laceration in a large cohort of women and to identify the characteristics associated with this complication. Data from all vaginal deliveries occurring between January 1996 and December 2004 at one institution were used to compare women with and without anal sphincter lacerations. Among 16,667 vaginal deliveries, 1,703 (10.