Pre-exposure Prophylaxis (PrEP) For Prevention of Human Immunodeficiency Virus: A Primary Practice Approach.

Acquired immunodeficiency syndrome (AIDS) is a chronic immune system disease caused by human immunodeficiency virus (HIV), first reported in 1981, and continues to interfere with the body's ability to fight infection and disease. There is no cure for HIV/AIDS, but medication can control infection and prevent disease progression. Pre-exposure prophylaxis (PrEP) taken orally, or as intramuscular injection, is safe and effective in reducing the chances of acquiring HIV.

Colonic and Anorectal Manifestations of Systemic Sclerosis.

Purpose Of Review: Systemic sclerosis is a chronic autoimmune disorder commonly involving the gastrointestinal tract, including the colon and anorectum. In this review, we summarize major clinical manifestations and highlight recent developments in physiology, diagnostics, and treatment.

Recent Findings: The exact pathophysiology of systemic sclerosis is unclear and likely multifactorial.