Family Process 1962-1969.

This is a personal recollection of the first 8 years of Family Process, the volumes published under the first Editor, Jay Haley, and strongly influenced by the Mental Research Institute at Palo Alto, of which Haley was a member. The later influence of the group's "double bind" hypothesis of schizophrenia is explored. Some ideas about the influence of theory on practice are suggested.

Some historical conditions of narrative work.

Written to honor the immense contribution of Michael White as a leader in the development of narrative therapy, this historical essay contrasts the origins of psychoanalysis, family therapy and narrative therapy. Changes in the understanding of therapeutic strategies, methods of training and supervision, styles of leadership, the involvement of audiences in the therapeutic and training processes, and conceptions of the nature of the mind are described. A style of direct demonstration of methods, especially of the formulation of questions, is important in narrative work.

Psychotherapy as a rite of passage.

Some psychotherapies may work because they resemble rites of passage. To explore this idea, this article describes an "individual" case of depression in which drug, cognitive, and narrative approaches fell short of effectiveness, and change occurred in a series of experiences that resemble a rite of passage. This resemblance is illuminated by examining two apparently quite different healing processes--Alcoholics Anonymous and multifamily group therapy in schizophrenia--to explore the elements they have in common with the case described: the acceptance of what Victor Turner called a liminal experience, and the importance of witnesses to the ritual support for that acceptance.

A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity.

The synthesis of pharmaceutical products frequently involves the use of reactive reagents and the formation of intermediates and by-products. Low levels of some of these may be present in the final drug substance and drug product as impurities. Such chemically reactive impurities may have at the same time the potential for unwanted toxicities including genotoxicity and carcinogenicity and hence can have an impact on product risk assessment.

Notes for a cultural history of family therapy.

The official history of family therapy describes its beginnings as a daring technical and philosophical departure from traditional individual treatment in the 1960s, inspired especially by the "system thinking" of Gregory Bateson. This celebrated origin story needs to be supplemented with a longer and larger history of both practice and thought about the family, and that is the subject of this article. The longer history goes back to the founding of social work by Mary Richmond, of pragmatism by William James, and of the organic view of social systems intervention by John Dewey.

The misuse and use of science in family therapy.

The wish to adopt ideas and metaphors from science can have a constricting effect on thinking about family therapy theory and practice. We describe three examples from the recent literature. The two problems describe: (a) borrowing the prestige and certainty of scientific ideas and metaphors and using them as cultural representations of reality, and (b) embracing certain philosophically comprehensive systems of thought.

Development of a cost-efficient psychogeriatrics service.

Various cost-efficient and space-efficient methods were used to expand outpatient services to the elderly at a teaching hospital's psychiatry clinic over a 2-year period. During this time the active treatment census of elderly patients more than doubled, to 185 patients. Only one enrolled patient required psychiatric hospitalization, and none required nursing home placement in the 2 years.

Measurements of social support in schizophrenia.

A selective review of the literature reveals some methods and instruments that show promise for the investigation of social support as a factor in the course and treatment of schizophrenia. Approaches are divided into social-psychological questionnaires, anthropological network studies, ethnographies, and clinical epidemiological investigations. Social support measures designed for the general population probably have little relevance in schizophrenia.

Family treatments of schizophrenia: background and state of the art.

Schizophrenia, as a failure to achieve maturity and independence, has always had distressing effects on a patient's family. Unfortunately, scientific theories that propose the family itself as a contributing factor have eroded the alliance between professionals and family members and added to the burden of family guilt. The initiative in designing family therapy for schizophrenia began among an early group of innovators who subscribed to strong family-theory ideologies.

Social support and schizophrenia.

This essay is an introduction to a review of the literature on measurement of social support in schizophrenia. It proposes a natural history for the development of the career of the schizophrenic in his social network. The dimensions of social support in this illness are shown to be specific to it, and different from what has been described for other illnesses such as depression.

Social networks and schizophrenia.

This artical begins with an introduction to social networks research and its practical importance in the understanding and treatment of schizophrenia, and concludes with a consideration of the experience, the phenomenology, of schizophrenia, from a social network point of view.

Social networks, the family, and the schizophrenic patient: introduction to the issue.

This article is an editor's introduction to the theme of a special issue of the Schizophrenia Bulletin. The origin of the social network concept is described. Ideology, morale, structure, and the larger social context are identified as aspects of the social network to be examined in future research.