Study of formulation of pharmaceutical solution form of paracetamol in the pediatric clinical practice.

Unlabelled: AIM of the study was selection of 2 different formulations of paracetamol of 2.5% (125 mg/5 mL) in the Pediatric practice. Paracetamol is widely used in the form of the syrup, with usual percentage of acting ingredient of 125 mg/5 mL.

Study of formulation of mild pharmaceutical forms of paracetamol in medical practice.

Introduction: Paracetamol is one of the most used antipyretic- analgesic preparation, which can be found in different pharmaceutical forms and in different doses. Due to its wide utilization in the clinical practice, determination of paracetamol in pharmaceutical formulation is of a great importance since that over dosage with paracetamol may cause the hepatic fulminant necroses and other toxic effects.

Material And Methods: Study has included two formulations of paracetamol suppositories with doses of 125 mg widely used in the paediatric practice.

Development ontogenesis of receptor tracheobronchial system in isolated preparations of pigs trachea in vitro.

Flow research of the development of receptor bronchial system was conducted in this work since the first day in 4th week of extra-uterine life, by following reactions of isolated tracheal rings in acetylcholine (Ach), histamine (Hist), and prostaglandin (PGF2-alfa) in concentrations of: 10(-4), 10(-3), 10(-2), 10(-1), mol/dm3, at piggy's of ages: 1 day, 1 week, 2 weeks and 4 weeks. Results shows that Ach causes reaction of smooth muscles since the first day of extra-uterine life in a significant way (p < 0.01).

Study of formulation of pharmaceutical forms of paracetamol in medical practice.

It is a well-known fact that tablets are the most ordinary medicines in daily practice, which along with capsules represents about 70% of pharmaceutical preparations. Experimenting with paracetamol tablets of 500 mg dose was scope of this study. Study of formulation, preparation, quality control, and follow-up of the paracetamol stability in tablets was conducted.

In vitro research of the alteration of neurons in vagal core in medulla oblongata at asphyxic deaths.

The aim of this study was to research the morphological changes of neurons in the vagus nerve nuclei in medulla oblongata in asphyxia related death cases. Morphological changes that were investigated were mainly in the dorsal motor respiratory center (DMRC), nucleus tractus solitarius (nTS) and nucleus ambigus (nA) in the medulla oblongata. In our research, the autopsy material from asphyxia related death cases was used from various etiologies: monoxide carbon (CO), liquid drowning, strangulation, electricity, clinical-pathological death, firing weapon, explosive weapon, sharp and blunt objects and death cases due to accident.