Publications by authors named "Becky Pik Ki Cheung"
Aim: Candida glabrata is a major pathogen in humans known to be intrinsically resistant to fluconazole. However, genotypic, phenotypic, and proteomic changes associated with reduced susceptibility to fluconazole are not properly understood. The aim of this study was to observe specific phenotypic, chromosomal, and proteomic alterations in a Candida glabrata strain sequentially exposed to fluconazole.
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- The study aimed to identify genes in the fetal heart that are crucial for heart muscle development and cell growth.
- Researchers used a technique called suppression subtractive hybridization on mRNA from fetal and adult heart cells to find differentially expressed genes.
- The results identified 39 fetal-dominant genes with potential roles in heart development, alongside various genes with unknown functions and high similarity to mitochondrial transcripts.