[Renin-secreting renal tumor. Apropos of a case with an ultrastructural and immunohistochemical study].

A case of renin-secreting tumor of the left kidney in a 36 year-old man with hypertension of five years duration is reported. The antihypertensive therapy was unsuccessful. Following nephrectomy, blood pressure returned to normal values and is still normal, seven years later.

[Clinical aspect and noninvasive diagnosis of cardiac myxomas].

The alteration of cardiac function in the presence of intracardiac tumors varies considerably according to their localization, size, and mode of insertion. Various cardiovascular diseases can be mimicked, e.g.

Giant-cell reaction in the small tubular bones. A light- and electron-microscopic study.

Light- and electron-microscopic investigations were performed in a case of cystic soap-bubble-like expansion of the shaft region of the second metatarsal bone. Morphologically, strongly cellular tissue with a closely packed net of osteoid trabeculae containing osteoblasts and a whorl-shaped spindle cell stroma with fibroblasts, fibrocytes, and irregularly scattered multinucleated giant cells of the osteoclast type were observed. After clinical and morphological exclusion of osteosarcoma, enchondroma, non-ossifying fibroma, osteoblastoma, osteoclastoma, and bone cysts the final diagnosis was giant-cell reaction of small tubular bone with unusual marked osteoid formation.

[Morphology of cavernous transformation of the portal vein (author's transl)].

Morphology of cavernous transformation of the portal vein is discussed on the basis of 5 case reports. On histological examination it can be shown, that in these cases a combination is present of chronic recanalized portal vein thrombosis and formation of paraportal hepatopetal collaterals. Formation of collaterals starts with new growth of primitive sinusoidal vessels originating from the portal vein and protruding into the paraportal tissue.

Premalignant lesions of the stomach.

The histopathogenesis of the three major types of gastric carcinoma--intestinal, diffuse and indeterminate--is reviewed, considering normal and abnormal cell kinetics of the gastric mucosa. Intestinalization is a precursor of intestinal-type carcinoma and is related to environmental factors. Diffuse gastric carcinoma originates from dysplasia of the neck of the gland and is of nonenvironmental, probably genetic, origin.

[Concomitant infarction of the right ventricle in patients with acute transmural myocardial infarction (author's transl)].

In 56 patients with acute transmural myocardial infarction hemodynamic parameters were studied. 21 patients proved to suffer from anterior infarction and 35 patients an inferior infarction. By clinical as well as by hemodynamic findings 10 patients out of the group of the 35 patients with inferior infarction were suspect of having a concomitant infarction of the right ventricle.

[Aggressive emperipolesis in chronic hepatitis (author's transl)].

The penetration and destruction of hepatocytes by lymphocytes (aggressive emperipolesis) has been described and examined quantitatively in biopsy specimens of chronic hepatitis. In 48 cases of chronic persistent hepatitis, the aggressive emperipolesis was rare and, obviously, not of great importance: sometimes there was no emperipolesis at all. In 36 cases of chronic aggressive hepatitis, however, emperioplesis was always evident, usually even to a very high extent.

[Morphological changes of the liver after chronic vinyl chloride intoxication (author's transl)].

The monomer vinyl chloride in its gaseous form is used as basic product for industrial synthesis of polyvinyl chloride; it does cause lesions of the liver depending on the dose and the time of exposure. Lesions found on histological examination are: 1. degenerative alterations of liver parenchyma; 2.