Genome Sequence of EM01, Isolated from Midgut and Responsible for Flacherie Disease in Silkworms Reared on an Artificial Diet.

The whole genome sequence of strain EM01 is reported here. The isolate proved to be the cause of flacherie in To date, the genomes of 11 other strains have been sequenced. EM01 is the only strain that displayed active pathological effects on its associated animal species.

Whole-Genome Sequences of Three Strains Isolated from Italian Cheeses in the Veneto Region.

We report here the genome sequences of three strains isolated from different cheeses in the Veneto region of Italy. The presented data aim at increasing the scarce genomic information available for this species, which is frequently encountered in fermented foods and appears to be a promising technological microorganism.

Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.

Pancreatic ductal adenocarcinoma (PDAC) is strikingly resistant to conventional therapeutic approaches. We previously demonstrated that the histone deacetylase-associated protein SIN3B is essential for oncogene-induced senescence in cultured cells. Here, using a mouse model of pancreatic cancer, we have demonstrated that SIN3B is required for activated KRAS-induced senescence in vivo.