Publications by authors named "Beatriz Saavedra"
Article Synopsis
- This text discusses a method for iodinating Weinreb amides, which are difficult to work with in chemical reactions, using an easily accessible catalyst.
- The process allows for selective iodination of both Weinreb amides and benzamides under mild conditions while being resistant to air and moisture.
- It highlights potential industrial uses and shows that the method can also be carried out using mechanochemical techniques, without affecting the reaction's effectiveness and selectivity.
Unnatural amino acids are valuable building blocks with numerous applications. Here, we present a quantitative technique for accessing mono-N-functionalized amino acids directly from unprotected substrates using alcohols as alkylating agents and an NHC-Ir(III) catalyst. We detail specific steps for catalyst preparation and application, as well as for catalyst recycling.
View Article and Find Full Text PDFA strong σ-donor mesoionic carbene ligand has been synthesized and applied to four different palladium-catalyzed cross-coupling transformations, proving the catalyst/medium compatibility and the increased activity of this system over previous reports in Deep Eutectic Solvent medium. Some cross-coupling processes could be carried out at room temperature and using aryl chlorides as starting materials. The possible implementation of multistep synthesis in eutectic mixtures has also been explored.
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