Publications by authors named "Beatriz Pinheiro Bezerra"
Six previously undescribed tropane alkaloids, designated as erythrobezerrines A-F, were isolated from the EtOH extract from the stem bark of Erythroxylum bezerrae Plowman. Their structures were elucidated based on the interpretation of the NMR and MS data and in some instances, confirmed by X-ray diffraction analysis. The cytotoxicity of the isolated compounds was evaluated against the cancer cell lines L929, PC-3, HCT-116, SNB-19 and NCI-H460, but only erythrobezerrine C showed moderate activity with IC values of 3.
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- A new complex, cis-[Ru(bpy)(Met)](PF), was created using L-methionine and 2,2'-bipyridine and was fully characterized.
- When exposed to blue and green light, this complex released methionine and produced another compound that interacted with DNA, resulting in DNA cleavage.
- The resulting compound demonstrated antibacterial properties, especially against certain bacteria, with enhanced effects when exposed to blue light, suggesting potential applications in drug development and peptide chemistry.