Publications by authors named "Beatriz Perez-Seoane"
Article Synopsis
- A study involving 13 hospitals in Spain examined the transmission of SARS-CoV-2 to newborns and included data from 177 infants exposed during pregnancy.
- Results showed 5.1% of the newborns tested positive for SARS-CoV-2, with 1.7% of cases attributed to intrauterine transmission and 3.4% to transmission during delivery or shortly after birth.
- Most infected newborns were either asymptomatic or had mild symptoms, and maternal factors did not significantly affect the risk of transmission, despite the presence of the virus in urine and meconium samples.
Objectives: To determine the time to reverse transcription-polymerase chain reaction (RT-PCR) negativity after the first positive RT-PCR test, factors associated with longer time to RT-PCR negativity, proportion of children seroconverting after proven severe acute respiratory syndrome coronavirus 2 infection, and factors associated with the lack of seroconversion.
Study Design: The Epidemiological Study of Coronavirus in Children of the Spanish Society of Pediatrics is a multicenter study conducted in Spanish children to assess the characteristics of coronavirus disease 2019. In a subset of patients, 3 serial RT-PCR tests on nasopharyngeal swab specimens were performed after the first RT-PCR test, and immunoglobulin G serology for severe acute respiratory syndrome coronavirus 2 antibodies was performed in the acute and follow-up (<14 and ≥14 days after diagnosis) phase.
Background: Knowledge about SARS-CoV-2 infection in pregnancy and newborns is scarce. The objective of this study is to analyse clinical and epidemiological characteristics of a cohort of women infected with SARS-CoV-2 during pregnancy and their newborns exposed to SARS-CoV-2 during gestation.
Methods: Multicentric observational study of Spanish hospitals from the GESNEO-COVD cohort, participants in RECLIP (Spanish Network of Paediatric Clinical Assays).
Article Synopsis
- Congenital cytomegalovirus infection (CMVc) affects a notable percentage of newborns, leading to issues such as low birth weight and length.
- A study observed 383 children with CMVc, comparing their growth patterns in the first two years to World Health Organization standards, revealing that about 10% had significant growth impairments by 24 months.
- Factors such as being symptomatic at birth, being premature, and having motor or neurocognitive impairments increased the risk of these growth issues, suggesting that growth impairment should be recognized as part of CMVc's clinical profile.
Aim: To describe and test a new technique to obtain midstream urine samples in newborns.
Design And Methods: This was a prospective feasibility and safety study conducted in the neonatal unit of University Infanta Sofía Hospital, Madrid. A new technique based on bladder and lumbar stimulation manoeuvres was tested over a period of 4 months in 80 admitted patients aged less than 30 days.