Publications by authors named "Beatriz Mateo"
Article Synopsis
- Metal nanoparticles, such as silver nanoparticles (AgNPs), show promise for cancer therapy due to their drug-like properties, but concerns about their toxicity to normal cells hinder clinical applications.
- This study focuses on the role of heat shock response (HSR) and integrated stress response (ISR) in the toxicity of AgNPs in triple-negative breast cancer (TNBC) compared to healthy mammary epithelial cells.
- The research found that using the ISR enhancer salubrinal with AgNPs selectively increased cancer cell death in TNBC without harming healthy cells, highlighting a potential strategy for safer cancer treatments.
Monte Carlo calculations are highly spread and settled practice to calculate brachytherapy sources dosimetric parameters. In this study, recommendations of the AAPM TG-43U1 report have been followed to characterize the Varisource VS2000 (192)Ir high dose rate source, provided by Varian Oncology Systems. In order to obtain dosimetric parameters for this source, Monte Carlo calculations with PENELOPE code have been carried out.
View Article and Find Full Text PDFChronic heart failure (CHF), especially affecting the right heart, frequently leads to malnutrition. If the latter is severe and is combined to other factors, it may lead to cardiac cachexia. This one is associated to increased mortality and lower survival of patients suffering from it.
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