Publications by authors named "Beatriz Isabel Garcia-Martinez"
Type 2 diabetes (T2D) affects a large part of the adult population and impairs its quality of life. Because of this, natural compounds with antioxidant, anti-inflammatory and hypoglycemic properties have been used as adjuvants. Among these compounds, resveratrol (RV) stands out, a polyphenol that has been studied in several clinical trials, the results of which are controversial.
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- A systematic review and meta-analysis of 17 studies were conducted to evaluate the hypoglycemic effects of resveratrol.
- Resveratrol significantly decreases glucose levels and improves HbA1c and insulin levels in subjects aged 45−59 years across various dosage ranges, but effects vary in individuals over 60.
- Despite these findings, there's insufficient evidence to recommend a specific therapeutic dose of resveratrol for managing blood sugar levels.
Resveratrol (RV) is a polyphenolic compound with antioxidant, anti-inflammatory, and hypoglycemic properties. Several in vitro and animal model studies have demonstrated the beneficial effects of RV; however, the results in humans are not conclusive. After a search of different databases, 32 studies were selected for this systematic review and 30 were included in the meta-analysis.
View Article and Find Full Text PDFThe Effect of 600 mg Alpha-lipoic Acid Supplementation on Oxidative Stress, Inflammation, and RAGE in Older Adults with Type 2 Diabetes Mellitus.
Oxid Med Cell Longev
January 2020
Alpha-lipoic acid (ALA) has been used as a dietary supplement at different doses in patients with diabetes mellitus type 2 (T2DM) due to its antioxidant, anti-inflammatory, and hypoglycemic effects. However, the reports on the effects of ALA are controversial. For this reason, the purpose of the present study was to determine the effect of 600 mg/day of ALA on the markers of oxidative stress (OxS) and inflammation and RAGE in older adults with T2DM.
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