Publications by authors named "Beatriz Farinha"
ACS Med Chem Lett
October 2023
Article Synopsis
- 12-Thiazole abietanes are special compounds that can help stop a brain problem called neuroinflammation by blocking a specific enzyme named hABHD16A.
- Scientists used different techniques to understand which parts of these compounds make them work better against hABHD16A while not affecting another enzyme, hABHD12.
- One compound showed to be super effective at blocking hABHD16A, but if it had a certain structure, it could accidentally block hABHD12 instead, which means the design of these compounds is really important for making new medicines.
