Prognostic value of neutrophil-to-lymphocyte ratio at diagnosis in colorectal cancer: propensity score analysis.

Introduction: baseline neutrophil-to-lymphocyte ratio (NLR) at the time of colorectal cancer (CRC) diagnosis has been proposed as a predictor of long-term survival. The aim of this study was to analyze its usefulness in a homogeneous population with control of the main confounding factors.

Methodology: observational study of 836 patients who underwent surgery for CRC.

Utility of a new prognostic score based on the Comprehensive Complication Index (CCI®) in patients operated on for colorectal cancer (S-CRC-PC score).

Background: Postoperative complications after colorectal cancer surgery have been associated with poor long-term prognosis. The aim of the present study was to investigate the prognostic impact of postoperative complications after colorectal cancer surgery assessed by the Comprehensive Complication Index (CCI®) and designing a new prognostic score based on this index.

Methods: This observational longitudinal study included a series of 604 patients who underwent colorectal surgery for cancer.

Mixed adenoneuroendocrine carcinoma of the colon - a complex and unique clinical duality.

In relation to the article "A case of mixed adenoneuroendocrine tumor of the colon", we would like to contribute a new case of this exceptional and biphasic clinical entity - the MANEC (mixed adenoneuroendocrine carcinoma). These tumors represent a mix of pathological components, are highly aggressive, and affect the gastrointestinal and pancreatobiliary tract. They are characterized by the dual presence of glandular and neuroendocrine epithelial elements, where each component represents at least 30 % of the tumor.

Metastatic choriocarcinoma in the proximal jejunum, an exceptional cause of massive upper gastrointestinal bleeding.

We present the clinical case of a 34-year-old woman with a history of stage IV choriocarcinoma, after her diagnostic debut two years ago, a hysterectomy and resection of the right single pulmonary nodule with anatomopathological confirmation of both as uterine choriocarcinoma and pulmonary nodule compatible with metastatic choriocarcinoma, subsequently the patient received chemotherapy treatment with stability of her disease until now.

Aganglionic megacolon in the adult. Urgent and surprising cause of intestinal occlusion.

In relation to the interesting article published recently in your scientific journal titled "Hirschsprung disease with debut in adult age as acute intestinal obstruction: a case report" , we would like to provide an exceptional case where the evolution of Hirschsprung's disease and an infrequent surgical complication developed in the long term are combined.

Bowel obstruction secondary to yeyunal intussusception due to gangliocytic paraganglioma.

Gangliocytic paraganglioma is an uncommon entity. The jejunum location is extremely rare: there are only five cases reported in medical literature. We present a case of gangliocytic paraganglioma.