Publications by authors named "Beatriz Aira C Jacob"
Article Synopsis
- The study investigates the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency among Thai individuals diagnosed with malaria, as well as among control subjects, to better inform malaria treatment options.
- Using phenotypic tests and high-resolution melting (HRM) analysis, researchers identified various G6PD mutations, discovering new double missense variants and assessing their biochemical impacts.
- Findings revealed a 6.13% prevalence of severe G6PD deficiency and an additional 15.20% with intermediate deficiency, with structural instability identified as a key factor affecting enzyme function linked to these mutations.
