Publications by authors named "Beatrix Willburger"
A total of 1075 Russians from the Russian part of Karelia were genotyped at high-resolution for the human leukocyte antigen loci HLA-A, -B, -C, -DRB1, -DQB1, and -DPB1 using next generation sequencing methods. The haplotypic and allelic profiles as well as Hardy-Weinberg proportions of this population sample were evaluated. As the most frequent 6-locus haplotype, A*03:01 g ∼ B*07:02 g ∼ C*07:02 g ∼ DRB1*15:01 g ∼ DQB1*06:02 g ∼ DPB1*04:01 g was identified with an estimated frequency of 3.
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- Leprosy was a common disease in Europe until the 16th century, caused by a germ called Mycobacterium leprae.
- Scientists studied old skeletons from Denmark to find out if they had this disease and managed to get complete DNA from 10 different bacteria, showing that the germs were diverse.
- They also discovered that a specific gene, which makes people more likely to get leprosy today, was also linked to medieval people, indicating they might have been at risk too.