Publications by authors named "Beatrice Schuepbach"
Ann Intensive Care
March 2024
Article Synopsis
- The study investigated whether volatile sedation with sevoflurane could protect organs in patients with severe COVID-19 lung injury experiencing a cytokine storm, particularly focusing on IL-6 levels.
- Conducted as a pilot trial in Switzerland, 60 patients requiring mechanical ventilation were randomly assigned to receive either sevoflurane or continuous intravenous sedation, with their outcomes analyzed at 28 days.
- Results showed no significant difference in primary outcomes such as mortality or persistent organ dysfunction between the two groups, but the sevoflurane group required fewer vasopressors and had higher reported acute kidney injury rates compared to controls.
