Publications by authors named "Beatrice Nuto Nobrega"
Background: The purpose of the study was to compare three-dimensional (3D) ultrasound semiautomatic antral follicle count (AFC) with two-dimensional (2D) ultrasound real-time AFC to evaluate patients with deep endometriosis and/or endometrioma submitted to ovarian stimulation (OS).
Methods: This was a retrospective cohort study assessing all women with documented diagnosis of deep endometriosis who underwent OS for assisted reproduction treatment. The primary outcome was the difference between AFC by semiautomatic 3D follicle count using 3D volume datasets and 2D ultrasound count with the number of oocytes retrieved at the end of the cycle.
Article Synopsis
- Concerns have been raised about the effects of controlled ovarian stimulation (COS) on endometrial receptivity and pregnancy outcomes in in-vitro fertilization (IVF), leading to the rise of the "freeze-all" strategy, where all embryos are frozen for later transfer.
- The freeze-all approach aims to avoid high hormone levels during COS and provides a more natural environment for embryo implantation, but initial benefits are mostly observed in specific patient groups.
- Despite its growing popularity, there is currently insufficient clinical evidence to support the routine use of the freeze-all strategy for a broader range of patients outside of those with specific risks, like ovarian hyperstimulation syndrome.
Preconditioning with a novel metallopharmaceutical NO donor in anesthetized rats subjected to brain ischemia/reperfusion.
Neurochem Res
April 2012
Rut-bpy is a novel nitrosyl-ruthenium complex releasing NO into the vascular system. We evaluated the effect of Rut-bpy (100 mg/kg) on a rat model of brain stroke. Forty rats were assigned to four groups (Saline solution [SS], Rut-bpy, SS+ischemia-reperfusion [SS+I/R] and Rut-bpy+ischemia-reperfusion [Rut-bpy+I/R]) with their mean arterial pressure (MAP) continuously monitored.
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