Publications by authors named "Beatrice Delepine"

The COVID-19 pandemic, driven by SARS-CoV-2, led authorities to recommend halting assisted reproductive technology programs, focusing instead on fertility preservation, for cancer patients. The presence of SARS-CoV-2 in semen remains controversial. This multicentric prospective cohort study, conducted across 12 university medical centers, aimed to determine if SARS-CoV-2 is present in spermatozoa/seminal plasma in cancer patients by RT-PCR and to assess its impact on standard semen parameters.

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Objective: To study karyotypes of >8,200 oocyte donor candidates in nulliparous or multiparous women compared with a reference population.

Design: A retrospective observational multicentric study.

Setting: University Hospital Centers.

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Article Synopsis
  • The study focuses on male fertility preservation (FP) through sperm banking for men aged 15-49 diagnosed with testicular cancer (TC) or lymphomas (L) in France in 2018.
  • It analyzed data from the French National Cancer Institute and sperm banking centers, estimating sperm banking rates of 41% for TC, 40% for Hodgkin L, and 7% for non-Hodgkin L among diagnosed men.
  • The findings suggest a need for improved patient education and awareness to increase sperm banking rates and assess factors leading to the lack of sperm preservation before gonadotoxic treatments.
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Background: Cancer treatments of the last decades improve the survival rate of children and adolescents. However, chemo- and radiotherapy result in gonadal damage, leading to acute ovarian failure and sterility. The preservation of fertility is now an integral part of care of children requiring gonadotoxic treatments.

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Male and female infertility has become a worldwide public health problem. The global obesity epidemic has paralleled a decrease in semen quality. Yet, the association between body mass index (BMI) and sperm parameters remains controversial.

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Article Synopsis
  • Many transgender individuals have high reproductive desires, but fertility preservation and sperm donation options in France were limited until recently due to restrictive Bioethics Law.
  • A national survey conducted at 28 reproductive technology centers revealed that a significant number of these centers provide services for fertility preservation, with 71.4% treating transgender patients.
  • Results indicated that transgender women are more likely to seek and achieve fertility preservation compared to transgender men, and a notable percentage of centers offer sperm donation services for couples including transgender men.
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Unlabelled: The purpose of the present multicenter study was to investigate whether an artificial insemination with donor sperm (AID) procedure after intra-couple intracytoplasmic sperm injection (ICSI) failure offers a significant chance of pregnancy and to identify prognostic factors for pregnancy after an AID procedure. An eleven-year retrospective multicenter study was conducted among 13 Centre d'Etude et de Conservation des Oeufs et du Sperme (CECOS) centers. A total of 319 couples having undergone an AID procedure after intra-conjugal ICSI failure were included in this study; a total of 1,159 AID and 1,011 intra-conjugal ICSI cycles were performed.

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