Publications by authors named "Beate Simon"
Article Synopsis
- The study focuses on how specific mutations in cancer lead to changes in protein expressions that contribute to malignant transformation, particularly in melanoma.
- Using advanced technology, researchers compared protein expression profiles in benign nevi and malignant BRAF-positive superficial spreading melanomas, noting significant differences especially in antigen levels.
- A key finding was the activation of the metalloproteinase ADAM10 by SPPL3 due to mutant BRAF, indicating that studying protein interactions and transformations can enhance our understanding of cancer progression.
