Publications by authors named "Beate Rauscher"
Article Synopsis
- Genetic predisposition is significant for early-onset chronic pancreatitis (CP), with some cases linked to genetic changes in digestive enzyme genes, while others remain unexplained.
- Researchers investigated CTRL, a chymotrypsin-like protease, by screening over 1,000 CP patients and 1,500 controls for genetic variants, analyzing their effects on enzyme secretion and activity.
- Although several CTRL variants were identified, many did not impact function or were equally present in both patients and controls, suggesting that CTRL is probably not a major contributor to the development of CP.
BackgroundThe exact epidemiology of tick-borne encephalitis virus (TBEV) infections is unknown because many TBEV infections have an influenza-like or asymptomatic course. Surveillance data are based on patients with any (predominantly neurological) symptoms that prompted diagnostic testing. Infection- and vaccine-induced antibodies against TBEV can be distinguished using an NS1 IgG ELISA.
View Article and Find Full Text PDFAims/hypothesis: Ingested protein is a well-recognised stimulus for glucagon-like peptide-1 (GLP-1) release from intestinal L cells. This study aimed to characterise the molecular mechanisms employed by L cells to detect oligopeptides.
Methods: GLP-1 secretion from murine primary colonic cultures and Ca(2+) dynamics in L cells were monitored in response to peptones and dipeptides.