Publications by authors named "Beata Winiarska"
Article Synopsis
- Ocular albinism type 1 (OA1) is linked to mutations in the GPR143 gene, affecting eye color and vision, with additional reports of late-onset hearing loss in some patients.
- A family study revealed an interstitial microdeletion on the X chromosome that includes not only GPR143 but also genes like TBL1X and SHROOM2, which might connect to infertility and hearing issues.
- The research suggests a potential link between the absence of TBL1X and hearing loss but emphasizes that more evidence is needed to confirm this and the relationship between the genetic deletion and male infertility.
Juvenile hormone (JH) regulates insect growth and development. JH present in the hemolymph is bound to juvenile hormone binding protein (hJHBP) which protects JH from degradation. In G.
View Article and Find Full Text PDFBackground: The CTLA-4 molecule is an important negative regulator of T cell activation. It is encoded on chromosome 2q33 and found to be associated with several allergic phenotypes including asthma. However, the association of CTLA-4 gene polymorphisms with allergic asthma is still controversial and therefore was the subject of this study.
View Article and Find Full Text PDFBackground: Eosinophils are important components of allergic inflammation. The immunoglobulin A (IgA) Fc receptor (FcalphaRI), encoded by the FCAR gene, is a possible candidate for eosinophil activation at mucosal surfaces, where IgA is abundant. Both elevated cell surface expression of FcalphaRI and increased avidity for IgA were described on eosinophils from allergic subjects.
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