Pulmonary blastoma in a pregnant woman: a case report and brief review of the literature.

Background: Pulmonary blastoma (PB) comprises a rare heterogeneous group of lung tumours typically containing immature epithelial and mesenchymal structures that imitate the embryonic lung tissue and extremely rarely occurs during pregnancy. Although cough and haemoptysis are the most common PB symptoms, they usually indicate other serious pregnancy-related complications.

Case Presentation: The article presents the unusual case of a 22-year-old pregnant woman diagnosed with PB during pregnancy.

Photodynamic therapy in the treatment of vulvar lichen sclerosus.

Background: Vulvar lichen sclerosus is a chronic and incurable disease that causes various unpleasant symptoms and serious consequences.

Objective: The purpose of the study was to assess the effectiveness of photodynamic therapy in the treatment of vulvar lichen sclerosus.

Methods: Participants in the study included 102 female patients aged 19-85 suffer from vulvar lichen sclerosus.

High frequency of allelic loss at the BRCA1 locus in ovarian cancers: clinicopathologic and molecular associations.

BRCA1 dysfunction may occur by different mechanisms that are rarely evaluated concomitantly. We aimed to analyze BRCA1 germline mutations, loss of heterozygosity (LOH) and promoter methylation in unselected ovarian carcinomas in the context of their clinicopathologic characteristics and other molecular changes. BRCA1 mutations were analyzed in 257 carcinomas using single-strand conformation polymorphism (SSCP), heteroduplex, and sequencing methods.

Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients.

Background: Survivin is an inhibitor of apoptosis and a regulator of mitotic progression. TP53 protein is a negative transcriptional regulator of survivin. The aim of our study was to evaluate the clinical significance of survivin expression in advanced stages ovarian cancer with respect to the TP53 status.

[Menstrual dysfunction in anorexia nervosa].

One of the symptoms of anorexia nervosa (a.n.) is cessation of pubescence or secondary amenorrhea.

Expression of vascular endothelial growth factor mRNA in human leiomyomas.

Aim: Growth factors play a major role in the pathogenesis of uterine myomas. The aim of this study was to evaluate vascular endothelial growth factor (VEGF) mRNA expression during leiomyoma growth at different phases of the menstrual cycle with RT-PCR.

Method: We studied 56 patients: 43 with myomas, 13 with healthy myometriums.

Therapeutic management of acoustic neurinoma during twin pregnancy: a case report.

Background: Acoustic neuromas belong to relatively rare illnesses in pregnant women. A gradual worsening of the symptoms presents a serious challenge for an obstetrician, neurosurgeon and anesthesiologist, who must work together to provide a successful outcome for mother and newborn.

Case: A 33-year-old woman presented with gradually progressing visual inacuity in the 30th week of pregnancy.

[From premature birth to cardiac surgery - severe heart failure due to infective endocarditis in pregnancy - a case report].

A 25-year-old woman, gravida 2, para 1, without any previous medical history was admitted to the hospital because of the signs and symptoms of fetal distress. After a caesarean section the woman developed an acute heart failure. Echocardiography demonstrated massive vegetations attached to aortic and mitral valves with their destruction.