Fat-body brummer lipase determines survival and cardiac function during starvation in .

The cross talk between adipose tissue and the heart has an increasing importance for cardiac function under physiological and pathological conditions. This study characterizes the role of fat body lipolysis for cardiac function in . Perturbation of the function of the key lipolytic enzyme, (), an ortholog of the mammalian (adipose triglyceride lipase) exclusively in the fly's fat body, protected the heart against starvation-induced dysfunction.