Fundus Changes in High Myopia in Relation to Axial Length of the Globe.

Purpose: The aim of the study is to correlate between axial length of the eyeball and fundus changes and to know its importance.

Materials And Methods: It was an observational study conducted for a duration of 1 year in patients with myopia more than 1 D and axial length more than 24 mm. A total of 100 eyes were included in the study and all underwent thorough fundus examination.

Deep Learning for Autism Diagnosis and Facial Analysis in Children.

In this paper, we introduce a deep learning model to classify children as either healthy or potentially having autism with 94.6% accuracy using Deep Learning. Patients with autism struggle with social skills, repetitive behaviors, and communication, both verbal and non-verbal.

A critical review of major mortality risk factors for all-cause mortality in first-episode schizophrenia: clinical and research implications.

A bibliographical search was performed to identify and evaluate the impact in first-episode schizophrenia of the major mortality risk factors as described by the World Health Organisation (2009). We found that at first diagnosis rates of diabetes were only slightly increased, although lipid abnormalities, mild hypertension and being overweight were commonly reported. Levels of drug and alcohol abuse were high, as were pre-diagnosis rates of smoking, physical inactivity and poor cardiorespiratory fitness.

Cardiovascular morbidity, mortality and pharmacotherapy in patients with schizophrenia.

Background: Patients with schizophrenia have excess cardiovascular morbidity and mortality. Previous studies suggest that this may be partly due to inadequate somatic treatment and care, such as non-optimal use of lipid-lowering and antihypertensive pharmacotherapy, but longitudinal studies on such aetiological pathways are scarce.

Method: We investigated the use of lipid-lowering and antihypertensive pharmacotherapy, and the risk of hospitalization for and death from coronary heart disease and stroke among patients with schizophrenia in a birth cohort of 12 939 subjects (Helsinki Birth Cohort Study).

Are there modifiable risk factors which will reduce the excess mortality in schizophrenia?

The 2009 World Health Organization report on global health risks identifies hypertension, smoking, raised glucose, physical inactivity, obesity and dyslipidaemia, in that order, as being the top six modifiable global mortality risk factors. Patients with schizophrenia have high levels of all these risk factors. There are a small number of studies showing that interventions can improve these, but prospective long-term studies are not available to show their impact on mortality.

The paradox of premature mortality in schizophrenia: new research questions.

The life expectancy of patients with schizophrenia is reduced by between 15 and 25 years. Those patients dying of natural causes die of the same diseases as in the general population. In 2009 the World Health Organization (WHO) identified underlying global risk factors for mortality in the general population.

A future pattern of psychiatric services and its educational implications: some suggestions.

Psychiatry has expanded rapidly as a medical discipline in the last two decades but has not always been able to recruit sufficient young doctors of ability to its ranks. In view of recent governmental and professional reports on future medical practice we set up a study group comprising members from academic, NHS, sub-specialty, community and in-training psychiatry to examine the present tasks, attractions and constraints within a career in psychiatry and propose possible improvements for further consideration. In marrying these views to foreseeable developments we are sensitive to the requirement to take into account both the needs of the community and the job satisfaction of the future psychiatrist.

Psycho-social stress, insomnia and temazepam: a sleep laboratory evaluation in a "general practice" sample.

Taking a population of women most of whom were about to seek medication from their general practitioner for stress-induced insomnia, this sleep laboratory study examined--both electro -physiologically and psychologically--the immediate impact of temazepam, at normal prescribed dosage, on sleep. The study was double-blind, controlled with random allocation. Temazepam 20 mg, prepared as a liquid in a soft gelatin capsule, reduced sleep latency and prolonged total sleep time.

The neuro-endocrine impact of 3-hydroxy-diazepam (temazepam) in women.

The benzodiazepines have been considered largely free of neuro-endocrine effect. However, in a double-blind, random assignment, placebo controlled study of six young women in the first half of their menstrual cycle oral temazepam (20 mg) was found to significantly lower plasma cortisol and raise plasma prolactin. The impact on cortisol was significant at 40 min and persisted for 3 h (P less than 0.

Sleep apnoea occurring only in REM (possible relevance of the case for some cot deaths).

A case of sleep apnoea occurring only within REM sleep in a 57-year-old man is described. It was successfully treated with clomipramine for a period. The patient probably had persistent phrenic nerve damage which accounted for, or contributed to, the phenomenon.

Solitary psychosis--three cases of monosymptomatic delusion of alimentary stench treated with behavioural psychotherapy.

Three cases of monosymptomatic delusion of alimentary stench are described. Each patient was referred for behaviour therapy as a last resort, after extensive medical investigation for halitosis or flatulence and failure of other psychiatric treatment. Two of the patients showed clinical improvement after treatment, sustained at follow-up.